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How to get fromNew Orleans to Saint Charlesby plane, bus (Greyhound), train, bus, or car

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There are 4 ways to get from New Orleans to Saint Charles by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Lambert–St. Louis International Airport (STL)plane plane MSY - STL
    4h 35m
    $406–906

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from New Orleans Bus Station to St Louis Bus Stationbus bus Greyhound US1173
    16h 5m
    $112–208

  3. Train, bus

    1. Take the train from New Orleans Union Passenger Terminal to Carbondaletrain train City of New Orleans
    2. Take the bus from Carbondale to St. Louisbus bus Amtrak Thruway Connecting Service
    17h 53m
    $222–465

  4. Drive 688.5 mi

    1. Drive from New Orleans to Saint Charlescar car 688.5 mi
    11h 12m
    $126–182

New Orleans to Saint Charles by bus and train (Greyhound)

Calendar7Weekly Services
Duration16h 5mAverage Duration
Ticket$112Cheapest Price
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Questions & Answers

Map of how to get from New Orleans to Saint Charles.ExpandLaunch map view
  • Distance: 631.5 mi
  • Duration: 4h 35m

What companies run services between New Orleans, LA, USA and Saint Charles, MO, USA?

Southwest Airlines and Delta fly from Louis Armstrong New Orleans International Airport (MSY) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, Greyhound USA operates a bus from New Orleans Bus Station to St Louis Bus Station once daily. Tickets cost $100–210 and the journey takes 14h 40m.

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