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How to get fromNew Orleans to Senecaby plane, taxi, bus, train (Amtrak), or car

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There are 6 ways to get from New Orleans to Seneca by plane, taxi, bus, train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport, taxi

    best
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Greenville–Spartanburg International Airport (GSP)plane plane MSY - GSP
    2. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    6h 5m
    $252–872

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Asheville Regional Airport (AVL)plane plane MSY - AVL
    2. Drive from Asheville-Airport-AVL to Senecacar car
    7h 17m
    $99–481

  3. Bus, taxi

    1. Take the bus from New Orleans Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Flying J - Commercebus bus
    3. Take the taxi from Flying J - Commerce to Senecataxi taxi
    13h 10m
    $218–413

  4. Train (Amtrak)

    1. Take the train from New Orleans Union Passenger Terminal to Clemson Amtrak Stationtrain train Crescent
    15h 42m
    $231–451

  5. Drive 582.3 mi

    1. Drive from New Orleans to Senecacar car 582.3 mi
    9h 41m
    $107–154

  6. Fly to Hartsfield-Jackson Atlanta International Airport, bus, taxi

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane MSY - ATL
    2. Take the bus from Atlanta to Flying J - Commercebus bus
    3. Take the taxi from Flying J - Commerce to Senecataxi taxi
    7h 44m
    $220–875

Louis Armstrong New Orleans International Airport (MSY) to Greenville–Spartanburg International Airport (GSP) flights

Calendar71Weekly Planes
Duration4h 23mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

Map of how to get from New Orleans to Seneca.ExpandLaunch map view
  • Distance: 639.9 mi
  • Duration: 6h 5m

What companies run services between New Orleans, LA, USA and Seneca, SC, USA?

Amtrak operates a train from New Orleans Union Passenger Terminal to Clemson Amtrak Station once daily. Tickets cost $200–430 and the journey takes 15h 30m.

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