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How to get fromNew Orleans to Sikestonby train, car, bus, taxi, or plane

Find Transport to Sikeston

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There are 7 ways to get from New Orleans to Sikeston by train, car, bus, taxi, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, drive (Amtrak)

    best
    1. Take the train from New Orleans Union Passenger Terminal to Fulton Amtrak Stationtrain train City of New Orleans
    2. Drive from Fulton Amtrak Station to Sikestoncar car
    12h 51m
    $184–364

  2. Drive 533.2 mi

    cheapest
    1. Drive from New Orleans to Sikestoncar car 533.2 mi
    8h 46m
    $98–141

  3. Bus, taxi

    1. Take the bus from New Orleans Bus Station to Cape Girardeaubus bus Greyhound US1173
    2. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    13h 15m
    $184–297

  4. Fly to Barkley Regional Airport, drive

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Barkley Regional Airport (PAH)plane plane MSY - PAH
    2. Drive from Barkley Regional Airport (PAH) to Sikestoncar car
    7h 49m
    $122–567

  5. Fly to Lambert–St. Louis International Airport, bus, taxi

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Lambert–St. Louis International Airport (STL)plane plane MSY - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    7h 51m
    $513–1,060

  6. Fly to Nashville, bus, drive

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Nashville (BNA)plane plane MSY - BNA
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Drive from Paducah Bus Station to Sikestoncar car
    8h 39m
    $966–1,011

  7. Fly to Cape Girardeau Municipal Airport, taxi

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Cape Girardeau Municipal Airport (CGI)plane plane MSY - CGI
    2. Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi taxi
    8h 1m
    $212–752

Louis Armstrong New Orleans International Airport (MSY) to Barkley Regional Airport (PAH) flights

Calendar21Weekly Planes
Duration5h 31mAverage Duration
Ticket$115Cheapest Price
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Questions & Answers

Map of how to get from New Orleans to Sikeston.ExpandLaunch map view
  • Distance: 595.4 mi
  • Duration: 12h 51m

What companies run services between New Orleans, LA, USA and Sikeston, MO, USA?

There is no direct connection from New Orleans to Sikeston. However, you can take the train to Fulton Amtrak Station then drive to Sikeston. Alternatively, you can take the bus to Cape Girardeau then take the taxi to Sikeston.

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