Rome2Rio

How to get fromNew Orleans to Simpsonvilleby plane, bus (Greyhound), train, bus, taxi, or car

Find Transport to Simpsonville

See all options

There are 6 ways to get from New Orleans to Simpsonville by plane, bus (Greyhound), train, bus, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louis Armstrong New Orleans International Airport to Greenville–Spartanburg International Airport

    best
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Greenville–Spartanburg International Airport (GSP)plane plane MSY - GSP
    5h 22m
    $157–797

  2. Fly Louis Armstrong New Orleans International Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Asheville Regional Airport (AVL)plane plane MSY - AVL
    2. Drive from Asheville-Airport-AVL to Simpsonvillecar car
    6h 22m
    $93–489

  3. Bus

    1. Take the bus from New Orleans Bus Station to Atlanta Bus Stationbus bus Greyhound US0602
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    13h 59m
    $147–219

  4. Train, bus, taxi

    1. Take the train from New Orleans Union Passenger Terminal to Charlotte Amtrak Stationtrain train
    2. Take the bus from Charlotte to Servicios Zapata - Spartanburgbus bus
    3. Take the taxi from Servicios Zapata - Spartanburg to Simpsonvilletaxi taxi
    22h 45m
    $287–579

  5. Drive  618.3 mi

    1. Drive from New Orleans to Simpsonvillecar car 618.3 mi
    10h 14m
    $113–163

  6. Train to Gulfport-Biloxi Regional Airport, fly to Greenville–Spartanburg International Airport

    1. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Greenville–Spartanburg International Airport (GSP)plane plane GPT - GSP
    5h 46m
    $166–702

Louis Armstrong New Orleans International Airport (MSY) to Greenville–Spartanburg International Airport (GSP) flights

Calendar91Weekly Planes
Duration4h 28mAverage Duration
Ticket$125Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from New Orleans to Simpsonville.ExpandLaunch map view
  • Distance: 603.1 mi
  • Duration: 5h 22m

What companies run services between New Orleans, LA, USA and Simpsonville, SC, USA?

Delta, Southwest Airlines, and American Airlines fly from Louis Armstrong New Orleans International Airport (MSY) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a bus from New Orleans Bus Station to Simpsonville via Atlanta Bus Station, Garnett Station, Doraville Station, Atlanta, and Taqueria Guadalajara - Greenville in around 13h 59m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There