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How to get fromNew Orleans to St. Louisby plane, bus (Greyhound), train, bus, or car

Find Transport to St. Louis

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There are 4 ways to get from New Orleans to St. Louis by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Lambert–St. Louis International Airport (STL)plane plane MSY - STL
    4h 11m
    $405–905

  2. Drive 676.1 mi

    cheapest
    1. Drive from New Orleans to St. Louiscar car 676.1 mi
    10h 58m
    $124–179

  3. Bus

    1. Take the bus from New Orleans Bus Station to St Louis Bus Stationbus bus Greyhound US1173
    14h 40m
    $150–220

  4. Train, bus

    1. Take the train from New Orleans Union Passenger Terminal to Carbondaletrain train City of New Orleans
    2. Take the bus from Carbondale to St. Louisbus bus Amtrak Thruway Connecting Service
    16h 28m
    $218–456

New Orleans to St. Louis by bus

Calendar14Weekly Buses
Duration14h 40mAverage Duration
Ticket$150Cheapest Price
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Questions & Answers

Map of how to get from New Orleans to St. Louis.ExpandLaunch map view
  • Distance: 631.4 mi
  • Duration: 4h 11m

What companies run services between New Orleans, LA, USA and St. Louis, MO, USA?

Southwest Airlines and Delta fly from Louis Armstrong New Orleans International Airport (MSY) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, Greyhound USA operates a bus from New Orleans Bus Station to St Louis Bus Station once daily. Tickets cost $110–210 and the journey takes 14h 40m. Jefferson Lines also services this route once daily.

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