Rome2Rio

How to get fromNew Orleans to St. Louis (Region)by plane, bus (Greyhound), train, bus, or car

Find Transport to St. Louis (Region)

See all options

There are 4 ways to get from New Orleans to St. Louis (Region) by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Lambert–St. Louis International Airport (STL)plane plane MSY - STL
    4h 11m
    $405–905
  2. Bus

    cheapest
    1. Take the bus from New Orleans Bus Station to St Louis Bus Stationbus bus Greyhound US1173
    14h 40m
    $110–220
  3. Train, bus

    1. Take the train from New Orleans Union Passenger Terminal to Carbondaletrain train City of New Orleans
    2. Take the bus from Carbondale to St. Louisbus bus Amtrak Thruway Connecting Service
    16h 28m
    $219–458
  4. Drive 676.1 mi

    1. Drive from New Orleans to St. Louis (Region)car car 676.1 mi
    10h 58m
    $124–179

New Orleans to St. Louis (Region) by bus

Calendar14Weekly Buses
Duration14h 40mAverage Duration
Ticket$110Cheapest Price
See schedules

Questions & Answers

What companies run services between New Orleans, LA, USA and St. Louis (Region), MO, USA?

Southwest Airlines and Delta fly from Louis Armstrong New Orleans International Airport (MSY) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, Greyhound-us operates a bus from New Orleans Bus Station to St Louis Bus Station once daily, and the journey takes 14h 40m. Greyhound USA also services this route once daily.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers