Rome2Rio

How to get fromNew Orleans to Winston-Salemby plane, bus (Greyhound), train (Amtrak), car, train, or bus

Find Transport to Winston-Salem

See all options

There are 8 ways to get from New Orleans to Winston-Salem by plane, bus (Greyhound), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louis Armstrong New Orleans International Airport to Piedmont Triad International Airport

    best
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Piedmont Triad International Airport (GSO)plane plane MSY - GSO
    6h 30m
    $171–825

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from New Orleans Bus Station to Atlanta Bus Stationbus bus Greyhound US0602
    2. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus Greyhound US0670
    15h 50m
    $117–231

  3. Train (Amtrak)

    1. Take the train from New Orleans Union Passenger Terminal to High Pointtrain train Crescent
    22h 24m
    $278–565

  4. Drive 775.4 mi

    1. Drive from New Orleans to Winston-Salemcar car 775.4 mi
    13h 17m
    $142–205

  5. Train to Gulfport-Biloxi Regional Airport, fly to Piedmont Triad International Airport

    1. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Piedmont Triad International Airport (GSO)plane plane GPT - GSO
    7h 1m
    $195–885

  6. Fly Louis Armstrong New Orleans International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Charlotte Douglas International Airport (CLT)plane plane MSY - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    6h 56m
    $143–748

  7. Fly Louis Armstrong New Orleans International Airport to Raleigh-Durham International Airport, bus

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Raleigh-Durham International Airport (RDU)plane plane MSY - RDU
    2. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    7h 54m
    $160–581

  8. Train to Gulfport-Biloxi Regional Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Charlotte Douglas International Airport (CLT)plane plane GPT - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    7h 21m
    $167–808

New Orleans to Winston-Salem by bus (Greyhound)

Calendar14Weekly Buses
Duration15h 50mAverage Duration
Ticket$117Cheapest Price
See schedules

Questions & Answers

Map of how to get from New Orleans to Winston-Salem.ExpandLaunch map view
  • Distance: 766.9 mi
  • Duration: 6h 30m

What companies run services between New Orleans, LA, USA and Winston-Salem, NC, USA?

Delta, American Airlines, and two other airlines fly from Louis Armstrong New Orleans International Airport (MSY) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a bus from New Orleans Bus Station to Winston Salem(Trans Center) via Atlanta Bus Station in around 15h 50m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers