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How to get fromNew Rochelle to Buffalo Depew Stationby train, bus, plane, train (Amtrak), bus (Flixbus), or car

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There are 8 ways to get from New Rochelle to Buffalo Depew Station by train, bus, plane, train (Amtrak), bus (Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus to Laguardia Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the train from New Rochelle to 125th Street - Harlemtrain train
    2. Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus bus
    3. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    3h 33m
    $106–633

  2. Drive 363.4 mi

    cheapest
    1. Drive from New Rochelle to Buffalo Depew Stationcar car 363.4 mi
    7h 18m
    $67–96

  3. Train

    1. Take the train from Yonkers Amtrak Station to Buffalo Depew Stationtrain train Maple Leaf / ...
    9h 37m
    $113–283

  4. Bus (Flixbus)

    1. Take the bus from New York Midtown to Buffalobus bus FlixBus 2686 / ...
    12h 20m
    $69–126

  5. Train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from New Rochelle to Grand Central Terminaltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    3h 45m
    $98–485

  6. Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from New Rochelle Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    3h 45m
    $102–514

  7. Fly Laguardia Airport to Rochester, train

    1. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    2. Take the train from Rochester to Buffalo Depew Stationtrain train
    5h 32m
    $144–951

  8. Train via Penn Station

    1. Take the train from New York Penn Station to Buffalotrain train VIA Rail
    10h 44m
    $116–296

New Rochelle to Buffalo Depew Station by bus and train

Calendar21Weekly Services
Duration9h 37mAverage Duration
Ticket$113Cheapest Price
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Questions & Answers

Map of how to get from New Rochelle to Buffalo Depew Station.ExpandLaunch map view
  • Distance: 313.6 mi
  • Duration: 3h 33m

What companies run services between New Rochelle, NY, USA and Buffalo Depew Station, NY, USA?

Amtrak operates a train from Yonkers Amtrak Station to Buffalo Depew Station twice daily. Tickets cost $110–260 and the journey takes 7h 35m. VIA Rail also services this route once daily. Alternatively, Flixbus USA operates a bus from New York Midtown to Buffalo 5 times a day. Tickets cost $60–110 and the journey takes 8h 35m.

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