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How to get fromNew Smyrna Beach to Florida Keysby taxi, plane, bus, car, train, bus (Greyhound), shuttle, or bus (Flixbus, Greyhound)

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There are 8 ways to get from New Smyrna Beach to Florida Keys by taxi, plane, bus, car, train, bus (Greyhound), shuttle, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Orlando Sanford, fly, bus

    best
    1. Take the taxi from New Smyrna Beach to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    3. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    4h 54m
    $185–430

  2. Drive 387 mi

    cheapest
    1. Drive from New Smyrna Beach to Florida Keyscar car 387 mi
    7h 10m
    $71–102

  3. Drive, train, bus

    1. Drive from New Smyrna Beach to Orlandocar car
    2. Take the train from Orlando to Miamitrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    11h 13m
    $93–256

  4. Taxi, train to Tampa, fly

    1. Take the taxi from New Smyrna Beach to Delandtaxi taxi
    2. Take the train from Deland to Tampatrain train
    3. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    10h 34m
    $256–650

  5. Bus via Fort Pierce South

    1. Take the bus from Edgewater to Fort Piercebus bus
    2. Take the bus from Fort Pierce to Miami Airportbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    12h 33m
    $87–165

  6. Bus, shuttle

    1. Take the bus from New Smyrna Beach to Miami Airport Stationbus bus Greyhound US0710s
    2. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus To the Keys
    13h 40m
    $204–278

  7. Bus (Greyhound)

    1. Take the bus from New Smyrna Beach to Miami Airport Stationbus bus Greyhound US0710s
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    14h 2m
    $73–138

  8. Bus #2

    1. Take the bus from Daytona Beach to Miami Airport Stationbus bus FlixBus 2431
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    17h 23m
    $72–130

New Smyrna Beach to Florida Keys by bus and foot

Calendar4Weekly Services
Duration17h 23mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

Map of how to get from New Smyrna Beach to Florida Keys.ExpandLaunch map view
  • Distance: 346.8 mi
  • Duration: 4h 54m

What companies run services between New Smyrna Beach, FL, USA and Florida Keys, FL, USA?

You can take a vehicle from New Smyrna Beach to Florida Keys via Edgewater, Fort Pierce, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 12h 33m.

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