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How to get fromNew Smyrna Beach to Key Largoby car, train, bus, bus (Greyhound), taxi, or plane

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There are 6 ways to get from New Smyrna Beach to Key Largo by car, train, bus, bus (Greyhound), taxi, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, train, bus

    best
    1. Drive from New Smyrna Beach to Orlandocar car
    2. Take the train from Orlando to Miamitrain train
    3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    7h 44m
    $62–206

  2. Drive 305.3 mi

    cheapest
    1. Drive from New Smyrna Beach to Key Largocar car 305.3 mi
    5h 17m
    $56–81

  3. Bus via Fort Pierce South

    1. Take the bus from Edgewater to Fort Piercebus bus
    2. Take the bus from Fort Pierce to Miami Airportbus bus
    3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    8h 43m
    $75–138

  4. Taxi, fly, bus

    1. Take the taxi from New Smyrna Beach to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    3. Take the bus from Key West Airport to Key Largo Bus Stopbus bus
    5h 49m
    $123–365

  5. Bus

    1. Take the bus from New Smyrna Beach to Miami Airport Stationbus bus Greyhound US0710s
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus Greyhound US0720s
    10h 11m
    $60–111

  6. Bus #2

    1. Take the bus from New Smyrna Beach to Miami Airport Stationbus bus Greyhound US0710s
    2. Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largobus bus 301
    11h 30m
    $61–103

Orlando Sanford (SFB) to Key West International Airport (EYW) flights

Calendar3Weekly Planes
Duration1h 18mAverage Duration
Ticket$39Cheapest Price
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Questions & Answers

Map of how to get from New Smyrna Beach to Key Largo.ExpandLaunch map view
  • Distance: 357.3 mi
  • Duration: 7h 44m

What companies run services between New Smyrna Beach, FL, USA and Key Largo, FL, USA?

You can take a vehicle from New Smyrna Beach to Key Largo Bus Stop via Edgewater, Fort Pierce, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, and Miami Airport Station in around 8h 43m.

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