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How to get fromNew Smyrna Beach to Knoxvilleby taxi, plane, train, bus, bus (Greyhound, Flixbus), or car

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There are 7 ways to get from New Smyrna Beach to Knoxville by taxi, plane, train, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, fly to Mcghee Tyson Airport

    best
    1. Take the taxi from New Smyrna Beach to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane plane SFB - TYS
    2h 37m
    $248–856

  2. Drive 611.2 mi

    cheapest
    1. Drive from New Smyrna Beach to Knoxvillecar car 611.2 mi
    11h 32m
    $112–162

  3. Taxi, train, bus via Farragut

    1. Take the taxi from New Smyrna Beach to Delandtaxi taxi
    2. Take the train from Deland to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    35h 19m
    $576–1,077

  4. Bus via Baltimore

    1. Take the bus from New Smyrna Beach to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Baltimore Downtown Bus Stationbus bus
    3. Take the bus from Baltimore Downtown Bus Station to New York Midtownbus bus
    4. Take the bus from New York to Knoxvillebus bus Nyc
    36h 38m
    $356–557

  5. Taxi, fly to Asheville Regional Airport, drive

    1. Take the taxi from New Smyrna Beach to Orlando-Sanford-Airport-SFBtaxi taxi
    2. Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane plane SFB - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    4h 33m
    $150–471

  6. Taxi, train, bus

    1. Take the taxi from New Smyrna Beach to Delandtaxi taxi
    2. Take the train from Deland to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    35h 23m
    $531–987

  7. Bus

    1. Take the bus from New Smyrna Beach to Jacksonvillebus bus
    2. Take the bus from Jacksonville to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    39h 12m
    $277–419

Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) flights

Calendar11Weekly Planes
Duration1h 38mAverage Duration
Ticket$120Cheapest Price
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Questions & Answers

Map of how to get from New Smyrna Beach to Knoxville.ExpandLaunch map view
  • Distance: 556.6 mi
  • Duration: 2h 37m

What companies run services between New Smyrna Beach, FL, USA and Knoxville, TN, USA?

You can take a vehicle from New Smyrna Beach to Knoxville via New Smyrna Beach, Jacksonville, Baltimore Downtown Bus Station, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 36h 38m.

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