There are 7 ways to get from New York Penn Station to Depew by plane, train, bus, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from John F. Kennedy International Airport
best- Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane JFK - BUF
3h 2m$101–489Bus via New York
cheapest- Take the bus from New York to Buffalobus Adt N816 / ...
10h 10m$64–276Train
- Take the train from New York Penn Station to Buffalotrain VIA Rail
8h 13m$127–294Drive 349.7 mi
- Drive from New York Penn Station to Depewcar 349.7 mi
7h 6m$64–93Fly from Newark Liberty International Airport
- Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane EWR - BUF
3h 5m$107–508Fly from Laguardia Airport
- Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane LGA - BUF
3h 28m$115–637Bus (Flixbus)
- Take the bus from New York Midtown to Buffalobus FlixBus 2686 / ...
10h 36m$77–124
New York Penn Station to Depew by foot and bus
Questions & Answers
The cheapest way to get from New York Penn Station to Depew is to drive which costs $60 - $95 and takes 7h 6m.
The fastest way to get from New York Penn Station to Depew is to fly which takes 3h 2m and costs $100 - $490.
No, there is no direct bus from New York Penn Station to Depew. However, there are services departing from New York and arriving at Broadway & Elwood Avenue via Ellicott Street & MTC Static. The journey, including transfers, takes approximately 10h 10m.
No, there is no direct train from New York Penn Station station to Depew. However, there are services departing from New York Penn Station and arriving at Buffalo via . The journey, including transfers, takes approximately 8h 13m.
The distance between New York Penn Station and Depew is 323 miles. The road distance is 351.7 miles.
The best way to get from New York Penn Station to Depew without a car is to train which takes 8h 13m and costs $120 - $300.
It takes approximately 3h 2m to get from New York Penn Station to Depew, including transfers.
New York Penn Station to Depew bus services, operated by Trailways, depart from New York station.
New York Penn Station to Depew train services, operated by VIA Rail, depart from New York Penn Station.
The best way to get from New York Penn Station to Depew is to fly which takes 3h 2m and costs $100 - $490. Alternatively, you can train, which costs $120 - $300 and takes 8h 13m, you could also bus via New York, which costs $60 - $280 and takes 10h 10m.
What companies run services between New York Penn Station, NY, USA and Depew, NY, USA?
JetBlue Airways and Delta fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF) every 3 hours. Alternatively, VIA Rail operates a train from New York Penn Station to Buffalo once daily. Tickets cost $110–290 and the journey takes 8h 9m.
- Website
- delta.com
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $70–450
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $90–600
- Website
- united.com
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $70–460
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $90–550
Flights from Laguardia Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 48m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–700
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $70–450
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport via Boston
- Ave. Duration
- 3h 34m
- When
- Every day
- Estimated price
- $95–550
- Website
- aa.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $90–600
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from New York Penn Station to Buffalo
- Ave. Duration
- 8h 9m
- Frequency
- Once daily
- Estimated price
- $110–290
- Website
- VIA Rail
- Escape
- $110–260
- Business
- $150–280
- Business Plus
- $160–290
- Economy
- $130–270
- Economy Plus
- $140–270
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from New York Midtown to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- Hourly
- Estimated price
- $70–130
- Schedules at
- Flixbus USA
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More Questions & Answers
New York Penn Station to Depew bus services, operated by Trailways, arrive at Buffalo station.
New York Penn Station to Depew train services, operated by VIA Rail, arrive at Buffalo station.
Yes, the driving distance between New York Penn Station to Depew is 352 miles. It takes approximately 7h 6m to drive from New York Penn Station to Depew.
There are 217+ hotels available in Depew.








