There are 7 ways to get from New York Penn Station to Des Moines by plane, bus (Flixbus, Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Newark Liberty International Airport
best- Fly from Newark Liberty International Airport (EWR) to Des Moines (DSM)plane EWR - DSM
4h 38m$197–848Bus
cheapest- Take the bus from New York Midtown to Chicago Bus Stationbus FlixBus N2641 / ...
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
24h 28m$193–329Train, bus
- Take the train from Ny Moynihan Train Hall At Penn Station to Chicago Union Stationtrain Lake Shore Limited / ...
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
27h 11m$355–724Drive 1,106 mi
- Drive from New York Penn Station to Des Moinescar 1,106 mi
18h 24m$202–292Fly from Laguardia Airport
- Fly from Laguardia Airport (LGA) to Des Moines (DSM)plane LGA - DSM
5h 3m$225–987Train to Philadelphia International Airport, fly
- Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain
- Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)plane PHL - DSM
5h 59m$261–1,720Train, bus via Galesburg
- Take the train from Ny Moynihan Train Hall At Penn Station to Croton-Harmon Amtrak Stationtrain
- Take the train from Croton-Harmon Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
- Take the bus from Galesburg to Des Moinesbus
30h$380–841
New York Penn Station to Des Moines by foot and bus
Questions & Answers
The cheapest way to get from New York Penn Station to Des Moines is to bus which costs $190 - $330 and takes 24h 28m.
The fastest way to get from New York Penn Station to Des Moines is to fly which takes 4h 38m and costs $190 - $850.
No, there is no direct bus from New York Penn Station to Des Moines. However, there are services departing from New York Midtown and arriving at Des Moines via Chicago Bus Station. The journey, including transfers, takes approximately 24h 28m.
The distance between New York Penn Station and Des Moines is 1040 miles. The road distance is 1112.5 miles.
The best way to get from New York Penn Station to Des Moines without a car is to bus which takes 24h 28m and costs $190 - $330.
It takes approximately 4h 38m to get from New York Penn Station to Des Moines, including transfers.
New York Penn Station to Des Moines bus services, operated by Flixbus USA, depart from New York Midtown station.
The best way to get from New York Penn Station to Des Moines is to fly which takes 4h 38m and costs $190 - $850. Alternatively, you can bus, which costs $190 - $330 and takes 24h 28m.
New York Penn Station to Des Moines bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Des Moines is 1h behind New York Penn Station. It is currently 12:10 AM in New York Penn Station and 11:10 PM in Des Moines.
What companies run services between New York Penn Station, NY, USA and Des Moines, IA, USA?
Allegiant Air, United Airlines, and two other airlines fly from Newark Liberty International Airport (EWR) to Des Moines (DSM) every 2 hours. Alternatively, you can take a vehicle from New York Penn Station to Des Moines via New York Midtown and Chicago Bus Station in around 24h 28m.
- Website
- aa.com
Flights from Newark Liberty International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $160–800
Flights from Newark Liberty International Airport to Des Moines via Charlotte
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $200–900
Flights from Laguardia Airport to Des Moines
- Ave. Duration
- 3h 8m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $200–950
Flights from Laguardia Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 47m
- When
- Every day
- Estimated price
- $200–950
Flights from Laguardia Airport to Des Moines via Reagan Washington
- Ave. Duration
- 5h 39m
- When
- Monday to Friday
- Estimated price
- $210–1,000
Flights from Philadelphia International Airport to Des Moines
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- $220–1,100
Flights from Philadelphia International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $220–1,100
Flights from Philadelphia International Airport to Des Moines via Charlotte
- Ave. Duration
- 5h 18m
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- $260–1,200
- Website
- united.com
Flights from Newark Liberty International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $160–800
Flights from Laguardia Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $200–950
Flights from Philadelphia International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $220–1,100
- Website
- delta.com
Flights from Newark Liberty International Airport to Des Moines via Detroit
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $160–800
Flights from Newark Liberty International Airport to Des Moines via Minneapolis
- Ave. Duration
- 6h 6m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–850
Flights from Laguardia Airport to Des Moines
- Ave. Duration
- 3h 1m
- When
- Every day
- Estimated price
- $200–950
Flights from Laguardia Airport to Des Moines via Detroit
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $200–950
Flights from Laguardia Airport to Des Moines via Minneapolis
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Philadelphia International Airport to Des Moines via Detroit
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $220–1,100
- Website
- southwest.com
Flights from Laguardia Airport to Des Moines via Chicago Midway
- Ave. Duration
- 5h 7m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $200–950
Flights from Philadelphia International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 4h 47m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $220–1,100
- Website
- allegiantair.com
Flights from Newark Liberty International Airport to Des Moines
- Ave. Duration
- 2h 55m
- When
- Monday and Friday
- Estimated price
- $160–800
Flights from Philadelphia International Airport to Des Moines
- Ave. Duration
- 2h 47m
- When
- Thursday and Sunday
- Estimated price
- $220–1,100
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Chicago Union Station
- Ave. Duration
- 19h 32m
- Frequency
- Once daily
- Estimated price
- $300–650
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to 30th Street Station
- Ave. Duration
- 1h 21m
- Frequency
- Every 30 minutes
- Estimated price
- $28–60
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Croton-Harmon Amtrak Station
- Ave. Duration
- 43 min
- Frequency
- Hourly
- Estimated price
- $10–22
- Website
- Amtrak
Train from Croton-Harmon Amtrak Station to Chicago Union Station
- Ave. Duration
- 18h 46m
- Frequency
- Once daily
- Estimated price
- $290–650
- Website
- Amtrak
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $50–110
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to 30th Street Station
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- $20–600
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $20–460
- First Class
- $130–600
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from New York Midtown to Chicago Bus Station
- Ave. Duration
- 16h 55m
- Frequency
- 4 times a day
- Estimated price
- $140–240
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 5 times a day
- Estimated price
- $50–95
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 5 times a day
- Estimated price
- $50–95
- Website
- Greyhound
Bus from Galesburg to Des Moines
- Ave. Duration
- 4h 55m
- Frequency
- Twice daily
- Estimated price
- $30–60
- Website
- Greyhound
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More Questions & Answers
Yes, the driving distance between New York Penn Station to Des Moines is 1112 miles. It takes approximately 18h 24m to drive from New York Penn Station to Des Moines.
Book your New York Penn Station to Des Moines bus tickets online with Omio and FlixBus.
There are 238+ hotels available in Des Moines.






