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How to get fromNew York Penn Station to Florenceby bus, train (Amtrak), car, plane, bus (Flixbus, Greyhound), or train

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There are 11 ways to get from New York Penn Station to Florence by bus, train (Amtrak), car, plane, bus (Flixbus, Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from New York, NY to Florence, SCbus bus Nyc
    13h 28m
    $86–131

  2. Train (Amtrak)

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Florence Stationtrain train Palmetto / ...
    14h 41m
    $190–410

  3. Drive 625.9 mi

    1. Drive from New York Penn Station to Florencecar car 625.9 mi
    11h 2m
    $115–165

  4. Fly Newark Liberty International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Newark Liberty International Airport (EWR) to Charlotte Douglas International Airport (CLT)plane plane EWR - CLT
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    8h 45m
    $252–670

  5. Bus via Fayetteville

    1. Take the bus from New York City Chinatown to Fayetteville Bus Stationbus bus FlixBus N2471 / ...
    2. Take the bus from Fayetteville Bus Station to Florence Bus Stationbus bus Greyhound US0642S / ...
    15h 9m
    $106–178

  6. Fly Newark Liberty International Airport to Raleigh-Durham International Airport, bus

    1. Fly from Newark Liberty International Airport (EWR) to Raleigh-Durham International Airport (RDU)plane plane EWR - RDU
    2. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    9h 10m
    $227–877

  7. Fly Laguardia Airport to Charlotte Douglas International Airport, bus

    1. Fly from Laguardia Airport (LGA) to Charlotte Douglas International Airport (CLT)plane plane LGA - CLT
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    9h 10m
    $160–659

  8. Fly Laguardia Airport to Wilmington International Airport, bus, train

    1. Fly from Laguardia Airport (LGA) to Wilmington International Airport (ILM)plane plane LGA - ILM
    2. Take the bus from Wilmington Cape Fear Public Transit to Fayetteville Bus Stationbus bus
    3. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train
    10h 7m
    $144–604

  9. Fly Laguardia Airport to Columbia, bus

    1. Fly from Laguardia Airport (LGA) to Columbia (CAE)plane plane LGA - CAE
    2. Take the bus from Columbia, SC to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    9h 55m
    $132–554

  10. Fly Laguardia Airport to Myrtle Beach, bus, train

    1. Fly from Laguardia Airport (LGA) to Myrtle Beach (MYR)plane plane LGA - MYR
    2. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    3. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    9h 46m
    $132–523

  11. Fly Newark Liberty International Airport to Myrtle Beach, bus, train

    1. Fly from Newark Liberty International Airport (EWR) to Myrtle Beach (MYR)plane plane EWR - MYR
    2. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    3. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    9h 31m
    $424–834

New York Penn Station to Florence by train (Amtrak)

Calendar14Weekly Trains
Duration14h 41mAverage Duration
Ticket$190Cheapest Price
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Questions & Answers

Map of how to get from New York Penn Station to Florence.ExpandLaunch map view
  • Distance: 682 mi
  • Duration: 13h 28m

What companies run services between New York Penn Station, NY, USA and Florence, SC, USA?

Wanda Coach operates a bus from New York, NY to Florence, SC 3 times a day. Tickets cost $85–130 and the journey takes 12h. Alternatively, Amtrak operates a train from Ny Moynihan Train Hall At Penn Station to Florence Station twice daily. Tickets cost $190–410 and the journey takes 14h 41m.

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