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How to get fromNew York Penn Station to Knoxvilleby plane, bus, car, or train

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There are 9 ways to get from New York Penn Station to Knoxville by plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Newark Liberty International Airport to Mcghee Tyson Airport

    best
    1. Fly from Newark Liberty International Airport (EWR) to Mcghee Tyson Airport (TYS)plane plane EWR - TYS
    3h 52m
    $205–847

  2. Fly Newark Liberty International Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Newark Liberty International Airport (EWR) to Asheville Regional Airport (AVL)plane plane EWR - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    5h 39m
    $107–432

  3. Bus via Farragut

    1. Take the bus from New York to Knoxvillebus bus Nyc
    13h 27m
    $183–253

  4. Drive 703.6 mi

    1. Drive from New York Penn Station to Knoxvillecar car 703.6 mi
    12h 1m
    $129–186

  5. Fly Laguardia Airport to Mcghee Tyson Airport

    1. Fly from Laguardia Airport (LGA) to Mcghee Tyson Airport (TYS)plane plane LGA - TYS
    4h 20m
    $233–1,036

  6. Train to Philadelphia International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS)plane plane PHL - TYS
    5h 17m
    $239–1,619

  7. Fly Laguardia Airport to Chattanooga Metropolitan Airport, drive

    1. Fly from Laguardia Airport (LGA) to Chattanooga Metropolitan Airport (CHA)plane plane LGA - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    5h 53m
    $206–1,044

  8. Fly Laguardia Airport to Asheville Regional Airport, drive

    1. Fly from Laguardia Airport (LGA) to Asheville Regional Airport (AVL)plane plane LGA - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    6h 5m
    $115–521

  9. Bus

    1. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    13h 31m
    $138–163

Newark Liberty International Airport (EWR) to Mcghee Tyson Airport (TYS) flights

Calendar56Weekly Planes
Duration4h 28mAverage Duration
Ticket$137Cheapest Price
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Questions & Answers

Map of how to get from New York Penn Station to Knoxville.ExpandLaunch map view
  • Distance: 656.6 mi
  • Duration: 3h 52m

What companies run services between New York Penn Station, NY, USA and Knoxville, TN, USA?

Allegiant Air, American Airlines, and two other airlines fly from Newark Liberty International Airport (EWR) to Mcghee Tyson Airport (TYS) every 4 hours. Alternatively, Wanda Coach operates a bus from New York to Knoxville once daily. Tickets cost $95–140 and the journey takes 11h 45m.

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