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How to get fromNew York Penn Station to St. Louisby plane, bus (Greyhound), train (Amtrak), car, or train

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There are 8 ways to get from New York Penn Station to St. Louis by plane, bus (Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Newark Liberty International Airport

    best
    1. Fly from Newark Liberty International Airport (EWR) to Lambert–St. Louis International Airport (STL)plane plane EWR - STL
    4h 50m
    $393–830

  2. Fly from John F. Kennedy International Airport

    cheapest
    1. Fly from John F. Kennedy International Airport (JFK) to Lambert–St. Louis International Airport (STL)plane plane JFK - STL
    5h 11m
    $137–621

  3. Bus (Greyhound)

    1. Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus bus Greyhound US0421
    23h 14m
    $150–300

  4. Train (Amtrak)

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Chicago Union Stationtrain train Lake Shore Limited / ...
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    25h 18m
    $390–819

  5. Drive 944.3 mi

    1. Drive from New York Penn Station to St. Louiscar car 944.3 mi
    16h 28m
    $173–249

  6. Fly from Laguardia Airport

    1. Fly from Laguardia Airport (LGA) to Lambert–St. Louis International Airport (STL)plane plane LGA - STL
    5h 3m
    $151–459

  7. Train to Philadelphia International Airport, fly

    1. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Lambert–St. Louis International Airport (STL)plane plane PHL - STL
    5h 58m
    $177–1,402

  8. Train to Long Island Mac Arthur Airport, fly

    1. Take the train from New York Penn Station to Central Isliptrain train
    2. Fly from Long Island Mac Arthur Airport (ISP) to Lambert–St. Louis International Airport (STL)plane plane ISP - STL
    8h 26m
    $159–733

New York Penn Station to St. Louis by foot and bus (Greyhound)

Calendar42Weekly Services
Duration23h 14mAverage Duration
Ticket$150Cheapest Price
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Questions & Answers

Map of how to get from New York Penn Station to St. Louis.ExpandLaunch map view
  • Distance: 897.5 mi
  • Duration: 4h 50m

What companies run services between New York Penn Station, NY, USA and St. Louis, MO, USA?

United Airlines, Delta, and Air Canada fly from Newark Liberty International Airport (EWR) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, Greyhound USA operates a bus from Port Authority Bus Terminal to St Louis Bus Station every 4 hours. Tickets cost $150–300 and the journey takes 23h.

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