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How to get fromNew York to Cleveland Clinicby train, plane, bus, train (Amtrak), car, or subway

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There are 8 ways to get from New York to Cleveland Clinic by train, plane, bus, train (Amtrak), car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Newark Liberty International Airport, fly

    best
    1. Take the train from New York Penn Station to Newark Airport Railroad Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Cleveland-Hopkins International Airport (CLE)plane plane EWR - CLE
    4h 12m
    $203–880

  2. Drive 449.5 mi

    cheapest
    1. Drive from New York to Cleveland Cliniccar car 449.5 mi
    8h 3m
    $82–119

  3. Bus

    1. Take the bus from New York to Cleveland, OHbus bus New York
    9h 11m
    $93

  4. Train (Amtrak)

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Cleveland Amtraktrain train Lake Shore Limited
    13h 14m
    $205–407

  5. Line 4 subway, bus to Laguardia Airport, fly

    1. Take the subway from 14 St-Union Sq to 125th Streetsubway subway
    2. Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus bus
    3. Fly from Laguardia Airport (LGA) to Cleveland-Hopkins International Airport (CLE)plane plane LGA - CLE
    4h 39m
    $129–714

  6. Train to John F. Kennedy International Airport, fly

    1. Take the train from New York Penn Station to Jamaicatrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Cleveland-Hopkins International Airport (CLE)plane plane JFK - CLE
    4h 35m
    $517–971

  7. Train to Philadelphia International Airport, fly

    1. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Cleveland-Hopkins International Airport (CLE)plane plane PHL - CLE
    5h 50m
    $197–1,032

  8. Bus via Port Authority Bus Terminal

    1. Take the bus from Port Authority Bus Terminal to Cleveland Bus Stationbus bus Greyhound US0420
    12h 53m

Newark Liberty International Airport (EWR) to Cleveland-Hopkins International Airport (CLE) flights

Calendar67Weekly Planes
Duration2h 47mAverage Duration
Ticket$78Cheapest Price
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Questions & Answers

Map of how to get from New York to Cleveland Clinic.ExpandLaunch map view
  • Distance: 433.8 mi
  • Duration: 4h 12m

What companies run services between New York, NY, USA and Cleveland Clinic, OH, USA?

Great Wall Bus operates a bus from New York to Cleveland, OH once daily. Tickets cost $90 and the journey takes 8h 30m. Alternatively, Amtrak operates a train from Ny Moynihan Train Hall At Penn Station to Cleveland Amtrak once daily. Tickets cost $200–410 and the journey takes 12h 13m.

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