There are 8 ways to get from New York to Depew by plane, train, bus, car, train (Amtrak), or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from John F. Kennedy International Airport
best- Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane JFK - BUF
3h 2m$106–519Bus
cheapest- Take the bus from New York to Buffalobus Adt N816 / ...
9h 58m$64–276Train
- Take the train from New York Penn Station to Buffalotrain VIA Rail
8h 13m$126–291Drive 347.7 mi
- Drive from New York to Depewcar 347.7 mi
7h 5m$64–92Fly from Newark Liberty International Airport
- Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane EWR - BUF
3h 5m$112–538Fly from Laguardia Airport
- Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane LGA - BUF
3h 28m$118–632Train via Galleria Driveway & Green Parking Entrance (Amtrak)
- Take the train from Ny Moynihan Train Hall At Penn Station to Buffalo Depew Stationtrain Empire Service / ...
10h 19m$147–287Bus via New York Midtown (Flixbus)
- Take the bus from New York Midtown to Buffalobus FlixBus N2686 / ...
10h 23m$72–116
New York to Depew by bus
Questions & Answers
The cheapest way to get from New York to Depew is to drive which costs $60 - $95 and takes 7h 5m.
The fastest way to get from New York to Depew is to fly which takes 3h 2m and costs $100 - $550.
No, there is no direct bus from New York to Depew. However, there are services departing from New York and arriving at Broadway & Elwood Avenue via Ellicott Street & MTC Static. The journey, including transfers, takes approximately 9h 58m.
No, there is no direct train from New York station to Depew. However, there are services departing from New York Penn Station and arriving at Buffalo via . The journey, including transfers, takes approximately 8h 13m.
The distance between New York and Depew is 323 miles. The road distance is 349.8 miles.
The best way to get from New York to Depew without a car is to train which takes 8h 13m and costs $120 - $300.
It takes approximately 3h 2m to get from New York to Depew, including transfers.
New York to Depew bus services, operated by Trailways, depart from New York station.
New York to Depew train services, operated by VIA Rail, depart from New York Penn Station.
The best way to get from New York to Depew is to fly which takes 3h 2m and costs $100 - $550. Alternatively, you can train, which costs $120 - $300 and takes 8h 13m, you could also bus, which costs $60 - $280 and takes 9h 58m.
What companies run services between New York, NY, USA and Depew, NY, USA?
JetBlue Airways and Delta fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF) every 3 hours. Alternatively, VIA Rail operates a train from New York Penn Station to Buffalo once daily. Tickets cost $110–280 and the journey takes 8h 9m.
- Website
- united.com
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $75–490
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $95–600
Flights from Laguardia Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $120–700
- Website
- delta.com
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $75–480
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $95–600
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $75–480
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport via Boston
- Ave. Duration
- 3h 34m
- When
- Every day
- Estimated price
- $100–600
- Website
- aa.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $95–600
- Phone
- +1 888 842-7245
- Website
- viarail.ca
Train from New York Penn Station to Buffalo
- Ave. Duration
- 8h 9m
- Frequency
- Once daily
- Estimated price
- $110–280
- Website
- https://www.viarail.ca/en
- Escape
- $110–260
- Business
- $150–270
- Business Plus
- $160–280
- Economy
- $130–260
- Economy Plus
- $140–270
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to Buffalo Depew Station
- Ave. Duration
- 8h 1m
- Frequency
- 4 times a day
- Estimated price
- $140–290
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from New York to Buffalo
- Ave. Duration
- 8h
- Frequency
- Every 4 hours
- Estimated price
- $60–280
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $60–260
- Flexible
- $110–280
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from New York Midtown to Buffalo
- Ave. Duration
- 8h 25m
- Frequency
- Every 4 hours
- Estimated price
- $65–120
- Schedules at
- flixbus.com
Want to know more about travelling around United States
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More Questions & Answers
New York to Depew bus services, operated by Trailways, arrive at Buffalo station.
New York to Depew train services, operated by VIA Rail, arrive at Buffalo station.
Yes, the driving distance between New York to Depew is 350 miles. It takes approximately 7h 5m to drive from New York to Depew.
Book your New York to Depew train tickets online with Omio.
There are 237+ hotels available in Depew.













