There are 10 ways to get from New York to Duke University Hospital by train, plane, bus, bus (Flixbus), train (Amtrak), car, subway, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Newark Liberty International Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus
best- Take the train from New York Penn Station to Newark Airport Railroad Stationtrain
- Fly from Newark Liberty International Airport (EWR) to Raleigh-Durham International Airport (RDU)plane EWR - RDU
- Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
- Take the bus from Regional Transit Center to Durham Stationbus
5h 2m$141–588Drive 484.8 mi
cheapest- Drive from New York to Duke University Hospitalcar 484.8 mi
8h 40m$83–120Bus (Flixbus)
- Take the bus from New York City Chinatown to Durhambus FlixBus N2471
11h 30m$92–134Train (Amtrak)
- Take the train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Stationtrain Carolinian
13h 11m$308–471Train to John F. Kennedy International Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus
- Take the train from New York Penn Station to Jamaicatrain
- Fly from John F. Kennedy International Airport (JFK) to Raleigh-Durham International Airport (RDU)plane JFK - RDU
- Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
- Take the bus from Regional Transit Center to Durham Stationbus
5h 13m$88–427Line 4 subway, bus to Laguardia Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus
- Take the subway from 14 St-Union Sq to 125th Streetsubway
- Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus
- Fly from Laguardia Airport (LGA) to Raleigh-Durham International Airport (RDU)plane LGA - RDU
- Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
- Take the bus from Regional Transit Center to Durham Stationbus
5h 26m$135–460Train to Long Island Mac Arthur Airport, fly to Raleigh-Durham International Airport
- Take the train from New York Penn Station to Central Isliptrain
- Fly from Long Island Mac Arthur Airport (ISP) to Raleigh-Durham International Airport (RDU)plane ISP - RDU
6h 35m$145–739Fly Laguardia Airport to Piedmont Triad International Airport, train
- Fly from Laguardia Airport (LGA) to Piedmont Triad International Airport (GSO)plane LGA - GSO
- Take the train from Greensboro to Durham Amtrak Stationtrain
6h 15m$142–569Train to Westchester County Airport, fly to Raleigh-Durham International Airport
- Take the train from Grand Central Terminal to White Plainstrain
- Fly from Westchester County Airport (HPN) to Raleigh-Durham International Airport (RDU)plane HPN - RDU
7h 7m$181–1,026Bus via Port Authority Bus Terminal (Greyhound)
- Take the bus from Port Authority Bus Terminal to Durhambus Greyhound US0670
13h 40m$106–155
New York to Duke University Hospital by bus and foot (Flixbus)
Comparing Your Travel Options
The cheapest way to get from New York to Duke University Hospital is to drive which costs $80 - $120 and takes 8h 40m.
The fastest way to get from New York to Duke University Hospital is to train and fly and bus and line 700 bus which takes 5h 2m and costs $140 - $600.
No, there is no direct bus from New York to Duke University Hospital. However, there are services departing from New York City Chinatown and arriving at Erwin Rd at Fulton St via Durham Station. The journey, including transfers, takes approximately 11h 30m.
No, there is no direct train from New York station to Duke University Hospital station. However, there are services departing from Ny Moynihan Train Hall At Penn Station and arriving at Durham Amtrak Station via . The journey, including transfers, takes approximately 13h 11m.
The distance between New York and Duke University Hospital is 452 miles. The road distance is 487.7 miles.
The best way to get from New York to Duke University Hospital without a car is to bus which takes 11h 30m and costs $90 - $140.
It takes approximately 5h 2m to get from New York to Duke University Hospital, including transfers.
New York to Duke University Hospital bus services, operated by Flixbus USA, depart from New York City Chinatown station.
New York to Duke University Hospital train services, operated by Amtrak, depart from Ny Moynihan Train Hall At Penn Station.
The best way to get from New York to Duke University Hospital is to bus which takes 11h 30m and costs $90 - $140. Alternatively, you can train, which costs $300 - $480 and takes 13h 11m.
What companies run services between New York, NY, USA and Duke University Hospital, NC, USA?
Flixbus USA operates a bus from New York City Chinatown to Durham 3 times a day. Tickets cost $85–140 and the journey takes 11h 10m. Alternatively, Amtrak operates a train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Station once daily. Tickets cost $300–470 and the journey takes 12h 51m.
- Website
- delta.com
Flights from Newark Liberty International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $80–500
Flights from John F. Kennedy International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- $65–400
Flights from John F. Kennedy International Airport to Raleigh-Durham International Airport via Reagan Washington
- Ave. Duration
- 4h 11m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $65–400
Flights from Laguardia Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- $100–650
Flights from Laguardia Airport to Piedmont Triad International Airport
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $75–470
- Website
- aa.com
Flights from John F. Kennedy International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 4m
- When
- Every day
- Estimated price
- $65–400
Flights from John F. Kennedy International Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $80–450
Flights from John F. Kennedy International Airport to Raleigh-Durham International Airport via Reagan Washington
- Ave. Duration
- 4h 37m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $65–400
Flights from Laguardia Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $100–650
Flights from Laguardia Airport to Piedmont Triad International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $75–470
Flights from Laguardia Airport to Piedmont Triad International Airport via Charlotte
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $90–500
Flights from Laguardia Airport to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 4h 4m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–470
Flights from Westchester County Airport to Raleigh-Durham International Airport via Reagan Washington
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $160–1,000
Flights from Westchester County Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $200–1,100
- Website
- united.com
Flights from Newark Liberty International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- $80–500
Flights from Newark Liberty International Airport to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $80–500
Flights from Laguardia Airport to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 3h 38m
- When
- Every day
- Estimated price
- $100–650
Flights from Laguardia Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $75–470
- Website
- flybreeze.com
Flights from Long Island Mac Arthur Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $280–1,700
Flights from Westchester County Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $390–2,300
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $65–400
- Website
- southwest.com
Flights from Long Island Mac Arthur Airport to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $120–700
- Phone
- +1 973-275-5555
- Website
- New Jersey Transit
Train from New York Penn Station to Newark Airport Railroad Station
- Ave. Duration
- 24 min
- Frequency
- Every 20 minutes
- Estimated price
- $16–20
- Website
- New Jersey Transit
- Website
- NJ Transit: World Cup 2026
- Adult Airport
- $16–20
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Durham Amtrak Station
- Ave. Duration
- 12h 51m
- Frequency
- Once daily
- Estimated price
- $300–470
- Website
- Amtrak
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $29–50
- Website
- Amtrak
- Phone
- +1-718-217-5477
- Website
- Long Island Rail Road
Train from New York Penn Station to Jamaica
- Ave. Duration
- 21 min
- Frequency
- Every 10 minutes
- Estimated price
- $5–10
- Website
- Long Island Rail Road
- Schedules at
- Long Island Rail Road Schedules
- Off-Peak
- $5–8
- Peak
- $6–10
Train from New York Penn Station to Central Islip
- Ave. Duration
- 1h 14m
- Frequency
- Every 30 minutes
- Estimated price
- $12–28
- Website
- Long Island Rail Road
- Schedules at
- Long Island Rail Road Schedules
- Off-Peak
- $12–18
- Peak
- $20–28
- Phone
- 877-690-5116
- Website
- MTA Homepage
Subway from 14 St-Union Sq to 125th Street
- Ave. Duration
- 15 min
- Frequency
- Every 5 minutes
- Estimated price
- $3
- Schedules at
- MTA Schedules
- Website
- MTA Homepage
- Website
- MTA: World Cup 2026
- Adult
- $3
- Phone
- +1 877.690.5114
- Website
- Metro North Railroad
Train from Grand Central Terminal to White Plains
- Ave. Duration
- 52 min
- Frequency
- Every 20 minutes
- Estimated price
- $9–15
- Website
- Metro North Railroad
- Schedules at
- Metro North Railroad Schedules
- Off-Peak
- $9–11
- Peak
- $13–15
- Phone
- +1 919 485 7433
- [email protected]
- Website
- gotriangle.org
Bus from RDU Airport at Terminal 2 to Regional Transit Center
- Ave. Duration
- 12 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- gotriangle.org
- Regular one-way fare
- $3
Bus from Regional Transit Center to Durham Station
- Ave. Duration
- 35 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- gotriangle.org
Bus from RDU Airport at Terminal 2 to Regional Transit Center
- Ave. Duration
- 12 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- gotriangle.org
- Regular one-way fare
- $3
Bus from Regional Transit Center to Durham Station
- Ave. Duration
- 35 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- gotriangle.org
Bus from RDU Airport at Terminal 2 to Regional Transit Center
- Ave. Duration
- 12 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- gotriangle.org
- Regular one-way fare
- $3
Bus from Regional Transit Center to Durham Station
- Ave. Duration
- 35 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- gotriangle.org
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from New York City Chinatown to Durham
- Ave. Duration
- 11h 10m
- Frequency
- 3 times a day
- Estimated price
- $85–140
- Schedules at
- Flixbus USA
- Phone
- 877-690-5116
- Website
- MTA
Bus from E 125 St/Lexington Av to Laguardia Rd/94 St
- Ave. Duration
- 24 min
- Frequency
- Every 10 minutes
- Estimated price
- $3–8
- Website
- MTA
- Schedules at
- MTA scheduled
- Website
- MTA: World Cup 2026
- Standard Fare
- $3–8
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Durham
- Ave. Duration
- 13h 20m
- Frequency
- Every 4 hours
- Estimated price
- $100–160
- Website
- Greyhound
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Booking & Getting There
New York to Duke University Hospital bus services, operated by Flixbus USA, arrive at Durham station.
New York to Duke University Hospital train services, operated by Amtrak, arrive at Durham Amtrak Station.
Yes, the driving distance between New York to Duke University Hospital is 488 miles. It takes approximately 8h 40m to drive from New York to Duke University Hospital.
There are 404+ hotels available in Duke University Hospital.


















