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How to get fromNew York to Murphysboroby plane, bus (Flixbus), train (Amtrak), car, bus, train, or bus (Greyhound, Amtrak, Flixbus)

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There are 10 ways to get from New York to Murphysboro by plane, bus (Flixbus), train (Amtrak), car, bus, train, or bus (Greyhound, Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Laguardia Airport to Williamson County Regional Airport

    best
    1. Fly from Laguardia Airport (LGA) to Williamson County Regional Airport (MWA)plane plane LGA - MWA
    7h 54m
    $161–671

  2. Bus via Nashville

    1. Take the bus from New York to Nashvillebus bus Nyc
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus FlixBus N2521
    20h 18m
    $167–231

  3. Train (Amtrak)

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Chicago Union Stationtrain train Lake Shore Limited / ...
    2. Take the train from Chicago Union Station to Carbondaletrain train Saluki / ...
    26h 12m
    $716–1,101

  4. Drive  951.2 mi

    1. Drive from New York to Murphysborocar car 951.2 mi
    17h
    $163–235

  5. Fly Newark Liberty International Airport to Williamson County Regional Airport

    1. Fly from Newark Liberty International Airport (EWR) to Williamson County Regional Airport (MWA)plane plane EWR - MWA
    7h 19m
    $162–559

  6. Fly Newark Liberty International Airport to Lambert–St. Louis International Airport, bus

    1. Fly from Newark Liberty International Airport (EWR) to Lambert–St. Louis International Airport (STL)plane plane EWR - STL
    2. Take the bus from St. Louis to Carbondalebus bus
    8h 18m
    $349–978

  7. Fly Laguardia Airport to Lambert–St. Louis International Airport, bus

    1. Fly from Laguardia Airport (LGA) to Lambert–St. Louis International Airport (STL)plane plane LGA - STL
    2. Take the bus from St. Louis to Carbondalebus bus
    8h 34m
    $223–500

  8. Train to Philadelphia International Airport, fly to Lambert–St. Louis International Airport, bus

    1. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Lambert–St. Louis International Airport (STL)plane plane PHL - STL
    3. Take the bus from St. Louis to Carbondalebus bus
    9h 20m
    $180–1,399

  9. Fly Laguardia Airport to Nashville, bus

    1. Fly from Laguardia Airport (LGA) to Nashville (BNA)plane plane LGA - BNA
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    10h
    $167–686

  10. Bus

    1. Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the bus from St. Louis to Carbondalebus bus Amtrak Thruway Connecting Service
    25h 35m
    $223–324

Laguardia Airport (LGA) to Williamson County Regional Airport (MWA) flights

Calendar45Weekly Planes
Duration8h 6mAverage Duration
Ticket$117Cheapest Price
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Comparing Your Travel Options

Map of how to get from New York to Murphysboro.ExpandLaunch map view
  • Distance: 867.4 mi
  • Duration: 7h 54m

What companies run services between New York, NY, USA and Murphysboro, IL, USA?

American Airlines and United Airlines fly from Laguardia Airport (LGA) to Williamson County Regional Airport (MWA) every 4 hours. Alternatively, you can take a bus from New York to Murphysboro via Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, and Carbondale Intermodal Station in around 20h 18m.

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