There are 11 ways to get from New York to West Seneca by train, plane, bus, bus (Flixbus), car, subway, bus (Greyhound), or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport, line 15 bus
best- Take the train from New York Penn Station to Jamaicatrain
- Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane JFK - BUF
- Take the bus from Lower Terrace & Adams Mark to Seneca Street & Cazenovia Parkwaybus
4h 52m$86–488Bus via Port Authority Bus Terminal
cheapest- Take the bus from Port Authority Bus Terminal to Buffalobus Greyhound US0215 / ...
9h 40m$59–250Train
- Take the train from New York Penn Station to Buffalotrain VIA Rail
8h 14m$144–313Bus (Flixbus)
- Take the bus from New York Midtown to Buffalobus FlixBus 2686 / ...
9h 35m$76–111Drive 351 mi
- Drive from New York to West Senecacar 351 mi
7h 6m$60–87Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport, line 15 bus
- Take the train from New York Penn Station to Newark Airport Railroad Stationtrain
- Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane EWR - BUF
- Take the bus from Lower Terrace & Adams Mark to Seneca Street & Cazenovia Parkwaybus
4h 56m$109–609Line 4 subway, bus to Laguardia Airport, fly to Buffalo Niagara International Airport, line 15 bus
- Take the subway from 14 St-Union Sq to 125th Streetsubway
- Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus
- Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane LGA - BUF
- Take the bus from Lower Terrace & Adams Mark to Seneca Street & Cazenovia Parkwaybus
5h 13m$113–741Fly Newark Liberty International Airport to Rochester, bus
- Fly from Newark Liberty International Airport (EWR) to Rochester (ROC)plane EWR - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
6h 6m$153–774Fly John F. Kennedy International Airport to Rochester, bus
- Fly from John F. Kennedy International Airport (JFK) to Rochester (ROC)plane JFK - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
6h 9m$125–613Fly Laguardia Airport to Rochester, bus
- Fly from Laguardia Airport (LGA) to Rochester (ROC)plane LGA - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
6h 19m$157–906Train via Lower Terrace & Adams Mark (Amtrak)
- Take the train from Ny Moynihan Train Hall At Penn Station to Buffalo Depew Stationtrain Empire Service / ...
10h 48m$244–371
New York to West Seneca by bus and foot (Flixbus)
Comparing Your Travel Options
The cheapest way to get from New York to West Seneca is to drive which costs $60 - $90 and takes 7h 6m.
The fastest way to get from New York to West Seneca is to train and fly and line 15 bus which takes 4h 52m and costs $85 - $490.
No, there is no direct bus from New York to West Seneca. However, there are services departing from New York Midtown and arriving at Seneca Street & Maywood Place via Lower Terrace & Adams Mark. The journey, including transfers, takes approximately 9h 35m.
No, there is no direct train from New York station to West Seneca. However, there are services departing from New York Penn Station and arriving at Buffalo via . The journey, including transfers, takes approximately 8h 14m.
The distance between New York and West Seneca is 334 miles. The road distance is 353 miles.
The best way to get from New York to West Seneca without a car is to train which takes 8h 14m and costs $140 - $320.
It takes approximately 4h 52m to get from New York to West Seneca, including transfers.
New York to West Seneca bus services, operated by Flixbus USA, depart from New York Midtown station.
New York to West Seneca train services, operated by VIA Rail, depart from New York Penn Station.
The best way to get from New York to West Seneca is to train which takes 8h 14m and costs $140 - $320. Alternatively, you can bus, which costs $75 - $120 and takes 9h 35m.
What companies run services between New York, NY, USA and West Seneca, NY, USA?
VIA Rail operates a train from New York Penn Station to Buffalo once daily. Tickets cost $110–280 and the journey takes 8h 1m. Alternatively, Flixbus USA operates a bus from New York Midtown to Buffalo hourly. Tickets cost $70–110 and the journey takes 8h 35m.
- Website
- delta.com
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $65–440
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $100–700
Flights from John F. Kennedy International Airport to Rochester
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $80–550
Flights from Laguardia Airport to Rochester
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $120–850
- Website
- united.com
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $80–550
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $100–600
Flights from Newark Liberty International Airport to Rochester
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $100–700
Flights from Newark Liberty International Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $130–800
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $65–440
Flights from John F. Kennedy International Airport to Rochester
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $80–550
- Website
- aa.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $100–700
- Phone
- +1-718-217-5477
- Website
- Long Island Rail Road
Train from New York Penn Station to Jamaica
- Ave. Duration
- 21 min
- Frequency
- Every 10 minutes
- Estimated price
- $5–10
- Website
- Long Island Rail Road
- Schedules at
- Long Island Rail Road Schedules
- Off-Peak
- $5–8
- Peak
- $6–10
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from New York Penn Station to Buffalo
- Ave. Duration
- 8h 1m
- Frequency
- Once daily
- Estimated price
- $110–280
- Website
- VIA Rail
- Escape
- $110–260
- Business
- $150–270
- Business Plus
- $160–280
- Economy
- $120–260
- Economy Plus
- $140–270
- Phone
- +1 973-275-5555
- Website
- New Jersey Transit
Train from New York Penn Station to Newark Airport Railroad Station
- Ave. Duration
- 24 min
- Frequency
- Every 20 minutes
- Estimated price
- $16–20
- Website
- New Jersey Transit
- Website
- NJ Transit: World Cup 2026
- Adult Airport
- $16–20
- Phone
- 877-690-5116
- Website
- MTA Homepage
Subway from 14 St-Union Sq to 125th Street
- Ave. Duration
- 15 min
- Frequency
- Every 5 minutes
- Estimated price
- $3
- Schedules at
- MTA Schedules
- Website
- MTA Homepage
- Website
- MTA: World Cup 2026
- Adult
- $3
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Buffalo Depew Station
- Ave. Duration
- 8h 1m
- Frequency
- 4 times a day
- Estimated price
- $230–370
- Website
- Amtrak
- Phone
- +1 716-855-7211
- [email protected]
- Website
- NFTA
Bus from Lower Terrace & Adams Mark to Seneca Street & Cazenovia Parkway
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- $2
- Website
- NFTA
Bus from Lower Terrace & Adams Mark to Seneca Street & Cazenovia Parkway
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- $2
- Website
- NFTA
Bus from Lower Terrace & Adams Mark to Seneca Street & Cazenovia Parkway
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- $2
- Website
- NFTA
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from New York Midtown to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- Hourly
- Estimated price
- $70–110
- Schedules at
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- $11–18
- Schedules at
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- $11–18
- Schedules at
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- $11–18
- Schedules at
- Flixbus USA
- Phone
- 877-690-5116
- Website
- MTA
Bus from E 125 St/Lexington Av to Laguardia Rd/94 St
- Ave. Duration
- 24 min
- Frequency
- Every 10 minutes
- Estimated price
- $3–8
- Website
- MTA
- Schedules at
- MTA scheduled
- Website
- MTA: World Cup 2026
- Standard Fare
- $3–8
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- $13–21
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- $13–21
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- $13–21
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Buffalo
- Ave. Duration
- 8h 40m
- Frequency
- Every 3 hours
- Estimated price
- $75–120
- Website
- Greyhound
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Port Authority Bus Terminal to Buffalo
- Saver
- $55–240
- Flexible
- $100–250
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Booking & Getting There
New York to West Seneca bus services, operated by Flixbus USA, arrive at Buffalo station.
New York to West Seneca train services, operated by VIA Rail, arrive at Buffalo station.
Yes, the driving distance between New York to West Seneca is 353 miles. It takes approximately 7h 6m to drive from New York to West Seneca.
Book your New York to West Seneca train tickets online with Omio.
There are 259+ hotels available in West Seneca.


























