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How to get fromNewYork-Presbyterian Hospital to Buffaloby subway, plane, bus, train (Amtrak), car, train, or bus (Flixbus)

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There are 10 ways to get from NewYork-Presbyterian Hospital to Buffalo by subway, plane, bus, train (Amtrak), car, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Subway to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the subway from 168 St to Howard Beach-JFK Airportsubway subway
    2. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    4h 37m
    $84–491

  2. Bus

    cheapest
    1. Take the bus from New York to Buffalobus bus Adt N816 / ...
    9h 30m
    $63–283

  3. Train via Yonkers

    1. Take the train from Yonkers Amtrak Station to Buffalotrain train Empire Service / ...
    9h 40m
    $118–293

  4. Drive 358.7 mi

    1. Drive from NewYork-Presbyterian Hospital to Buffalocar car 358.7 mi
    7h 11m
    $66–95

  5. Bus to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from W 125 St/Saint Nicholas Av to Laguardia Rd/94 Stbus bus
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    4h 20m
    $98–640

  6. Line 1 subway, train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the subway from 168 St-Washington Hts to 34 St-Penn Stationsubway subway
    2. Take the train from New York Penn Station to Newark Airport Railroad Stationtrain train
    3. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    4h 34m
    $95–520

  7. Fly Laguardia Airport to Rochester, bus

    1. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 58m
    $130–705

  8. Fly Newark Liberty International Airport to Rochester, bus

    1. Fly from Newark Liberty International Airport (EWR) to Rochester (ROC)plane plane EWR - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 13m
    $522–1,675

  9. Train

    1. Take the train from New York Penn Station to Buffalotrain train VIA Rail
    9h 55m
    $113–293

  10. Bus via W 31 St/6 Av (Flixbus)

    1. Take the bus from New York Midtown to Buffalobus bus FlixBus N2686 / ...
    10h 55m
    $73–127

NewYork-Presbyterian Hospital to Buffalo by foot, subway, and bus

Calendar45Weekly Services
Duration9h 30mAverage Duration
Ticket$63Cheapest Price
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Questions & Answers

Map of how to get from NewYork-Presbyterian Hospital to Buffalo.ExpandLaunch map view
  • Distance: 339.9 mi
  • Duration: 4h 37m

What companies run services between NewYork-Presbyterian Hospital, NY, USA and Buffalo, NY, USA?

Trailways operates a bus from New York to Buffalo every 4 hours. Tickets cost $60–280 and the journey takes 8h. Alternatively, Amtrak operates a train from Yonkers Amtrak Station to Buffalo twice daily. Tickets cost $130–280 and the journey takes 7h 58m. VIA Rail also services this route once daily.

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