There are 9 ways to get from NewYork-Presbyterian Lower Manhattan Hospital to Buffalo by subway, plane, bus, train, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Subway to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport
best- Take the subway from Fulton St to Howard Beach-JFK Airportsubway
- Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane JFK - BUF
4h 3m$84–491Bus
cheapest- Take the bus from New York to Buffalobus Adt N816 / ...
9h 18m$63–283Train
- Take the train from New York Penn Station to Buffalotrain VIA Rail
9h 37m$123–293Drive 356.5 mi
- Drive from NewYork-Presbyterian Lower Manhattan Hospital to Buffalocar 356.5 mi
7h 15m$66–94Line 4 subway, bus to Laguardia Airport, fly to Buffalo Niagara International Airport
- Take the subway from Brooklyn Bridge-City Hall to 125th Streetsubway
- Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus
- Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane LGA - BUF
4h 22m$98–640Line 2 subway, train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport
- Take the subway from Fulton St to 34 St-Penn Stationsubway
- Take the train from New York Penn Station to Newark Airport Railroad Stationtrain
- Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane EWR - BUF
4h 13m$95–520Fly Newark Liberty International Airport to Rochester, bus
- Fly from Newark Liberty International Airport (EWR) to Rochester (ROC)plane EWR - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
5h 28m$522–1,674Fly Laguardia Airport to Rochester, bus
- Fly from Laguardia Airport (LGA) to Rochester (ROC)plane LGA - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
5h 36m$130–704Bus via New York Midtown (Flixbus)
- Take the bus from New York Midtown to Buffalobus FlixBus 2686 / ...
9h 42m$73–123
NewYork-Presbyterian Lower Manhattan Hospital to Buffalo by foot, subway, and bus
Questions & Answers
The cheapest way to get from NewYork-Presbyterian Lower Manhattan Hospital to Buffalo is to drive which costs $65 - $95 and takes 7h 15m.
The fastest way to get from NewYork-Presbyterian Lower Manhattan Hospital to Buffalo is to subway and fly which takes 4h 3m and costs $80 - $500.
No, there is no direct bus from NewYork-Presbyterian Lower Manhattan Hospital to Buffalo. However, there are services departing from New York and arriving at Buffalo via . The journey, including transfers, takes approximately 9h 18m.
No, there is no direct train from NewYork-Presbyterian Lower Manhattan Hospital to Buffalo. However, there are services departing from Fulton St and arriving at Buffalo via New York Penn Station. The journey, including transfers, takes approximately 9h 37m.
The distance between NewYork-Presbyterian Lower Manhattan Hospital and Buffalo is 332 miles. The road distance is 358.6 miles.
The best way to get from NewYork-Presbyterian Lower Manhattan Hospital to Buffalo without a car is to bus which takes 9h 18m and costs $60 - $290.
It takes approximately 4h 3m to get from NewYork-Presbyterian Lower Manhattan Hospital to Buffalo, including transfers.
NewYork-Presbyterian Lower Manhattan Hospital to Buffalo bus services, operated by Trailways, depart from New York station.
NewYork-Presbyterian Lower Manhattan Hospital to Buffalo train services, operated by VIA Rail, depart from New York Penn Station.
The best way to get from NewYork-Presbyterian Lower Manhattan Hospital to Buffalo is to bus which takes 9h 18m and costs $60 - $290. Alternatively, you can train, which costs $120 - $300 and takes 9h 37m.
What companies run services between NewYork-Presbyterian Lower Manhattan Hospital, NY, USA and Buffalo, NY, USA?
Trailways operates a bus from New York to Buffalo every 4 hours. Tickets cost $60–280 and the journey takes 8h. Alternatively, VIA Rail operates a train from New York Penn Station to Buffalo once daily. Tickets cost $120–290 and the journey takes 8h 24m.
- Website
- united.com
Flights from Laguardia Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 48m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–700
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $70–460
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $90–550
Flights from Newark Liberty International Airport to Rochester
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $75–500
Flights from Newark Liberty International Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $100–600
Flights from Laguardia Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $130–750
- Website
- delta.com
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $70–450
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $90–600
Flights from Laguardia Airport to Rochester
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $95–650
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $70–450
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport via Boston
- Ave. Duration
- 3h 34m
- When
- Every day
- Estimated price
- $95–550
- Website
- aa.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $90–600
- Phone
- 877-690-5116
- Website
- MTA Homepage
Subway from Fulton St to Howard Beach-JFK Airport
- Ave. Duration
- 35 min
- Frequency
- Every 15 minutes
- Estimated price
- $3
- Schedules at
- MTA Schedules
- Website
- MTA Homepage
- Website
- MTA: World Cup 2026
- Adult
- $3
Subway from Brooklyn Bridge-City Hall to 125th Street
- Ave. Duration
- 20 min
- Frequency
- Every 5 minutes
- Estimated price
- $3
- Schedules at
- MTA Schedules
- Website
- MTA Homepage
- Website
- MTA: World Cup 2026
- Adult
- $3
Subway from Fulton St to 34 St-Penn Station
- Ave. Duration
- 11 min
- Frequency
- Every 5 minutes
- Estimated price
- $3
- Schedules at
- MTA Schedules
- Website
- MTA Homepage
- Website
- MTA: World Cup 2026
- Adult
- $3
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from New York Penn Station to Buffalo
- Ave. Duration
- 8h 24m
- Frequency
- Once daily
- Estimated price
- $120–290
- Website
- VIA Rail
- Escape
- $120–260
- Business
- $160–280
- Business Plus
- $170–290
- Economy
- $130–270
- Economy Plus
- $140–280
- Phone
- +1 973-275-5555
- Website
- New Jersey Transit
Train from New York Penn Station to Newark Airport Railroad Station
- Ave. Duration
- 24 min
- Frequency
- Every 20 minutes
- Estimated price
- $15–19
- Website
- New Jersey Transit
- Website
- NJ Transit: World Cup 2026
- Adult Airport
- $15–19
- Phone
- 877-690-5116
- Website
- MTA
Bus from E 125 St/Lexington Av to Laguardia Rd/94 St
- Ave. Duration
- 24 min
- Frequency
- Every 10 minutes
- Estimated price
- $3–8
- Website
- MTA
- Schedules at
- MTA scheduled
- Website
- MTA: World Cup 2026
- Standard Fare
- $3–8
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- $11–19
- Schedules at
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- $11–19
- Schedules at
- Flixbus USA
Bus from New York Midtown to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- Hourly
- Estimated price
- $70–120
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- $11–21
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- $11–21
- Website
- Greyhound
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More Questions & Answers
NewYork-Presbyterian Lower Manhattan Hospital to Buffalo bus services, operated by Trailways, arrive at Buffalo station.
NewYork-Presbyterian Lower Manhattan Hospital to Buffalo train services, operated by VIA Rail, arrive at Buffalo station.
Yes, the driving distance between NewYork-Presbyterian Lower Manhattan Hospital to Buffalo is 359 miles. It takes approximately 7h 15m to drive from NewYork-Presbyterian Lower Manhattan Hospital to Buffalo.
There are 235+ hotels available in Buffalo.
















