Rome2Rio

How to get fromNewark Airport (EWR) to Mayo Clinicby plane, bus (Flixbus, Greyhound), train, bus, bus (Greyhound), or car

Find Transport to Mayo Clinic

See all options

There are 10 ways to get from Newark Airport (EWR) to Mayo Clinic by plane, bus (Flixbus, Greyhound), train, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Newark Liberty International Airport to Rochester

    best
    1. Fly from Newark Liberty International Airport (EWR) to Rochester (RST)plane plane EWR - RST
    6h 24m
    $96–495

  2. Fly Laguardia Airport to Rochester

    1. Fly from Laguardia Airport (LGA) to Rochester (RST)plane plane LGA - RST
    9h 22m
    $140–684

  3. Bus

    1. Take the bus from Newark Penn Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to Rochesterbus bus
    27h 8m
    $205–341

  4. Train, bus via Milwaukee

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Croton-Harmon Amtrak Stationtrain train
    2. Take the train from Croton-Harmon Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    4. Take the bus from Milwaukee to Rochesterbus bus
    31h 24m
    $406–804

  5. Fly Newark Liberty International Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Newark Liberty International Airport (EWR) to Minneapolis–Saint Paul International Airport (MSP)plane plane EWR - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    5h 45m
    $207–902

  6. Fly Newark Liberty International Airport to Dane County Regional Airport-Truax Field, bus

    1. Fly from Newark Liberty International Airport (EWR) to Dane County Regional Airport-Truax Field (MSN)plane plane EWR - MSN
    2. Take the bus from Madison to Rochesterbus bus
    9h 12m
    $178–717

  7. Train, bus

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Croton-Harmon Amtrak Stationtrain train
    2. Take the train from Croton-Harmon Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochesterbus bus
    33h 11m
    $458–958

  8. Bus via Baltimore

    1. Take the bus from Newark Penn Station to Baltimorebus bus
    2. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    35h 38m
    $227–450

  9. Train, bus #2

    1. Take the train from Newark Penn Station to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    39h 49m
    $417–885

  10. Drive 1,127 mi

    1. Drive from Newark Airport (EWR) to Mayo Cliniccar car 1,127 mi
    18h 47m
    $206–298

Newark Airport (EWR) to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration27h 8mAverage Duration
Ticket$205Cheapest Price
See schedules

Questions & Answers

Map of how to get from Newark Airport (EWR) to Mayo Clinic.ExpandLaunch map view
  • Distance: 969.1 mi
  • Duration: 6h 24m

What companies run services between Newark Airport (EWR), USA and Mayo Clinic, MN, USA?

United Airlines, American Airlines, and Delta fly from Newark Liberty International Airport (EWR) to Rochester (RST) every 3 hours. Alternatively, you can take a bus from Terminal B to Mayo Clinic via Newark Penn Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 27h 8m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers