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How to get fromNiagara Falls to Lexingtonby bus, plane, bus (Greyhound), train (Amtrak), car, train, or bus (Flixbus)

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There are 8 ways to get from Niagara Falls to Lexington by bus, plane, bus (Greyhound), train (Amtrak), car, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Buffalo Niagara International Airport, fly

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    4h 39m
    $75–419

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    14h 6m
    $74–149

  3. Train

    1. Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain train Maple Leaf / ...
    2. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    14h 14m
    $163–473

  4. Drive 465.6 mi

    1. Drive from Niagara Falls to Lexingtoncar car 465.6 mi
    8h 12m
    $107–154

  5. Train to Rochester, fly

    1. Take the train from Niagara Falls Amtrak Station to Rochestertrain train
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    5h 43m
    $110–610

  6. Train to Toronto Island Airport, fly

    1. Take the train from Niagara Falls to Toronto Union Stationtrain train
    2. Fly from Toronto Island Airport (YTZ) to Boston Logan Airport (BOS)plane plane YTZ - BOS
    7h 11m
    $137–653

  7. Train to Toronto Pearson International Airport, fly

    1. Take the train from Niagara Falls to Toronto Union Stationtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Boston Logan Airport (BOS)plane plane YYZ - BOS
    7h 42m
    $137–723

  8. Bus via Ithaca (Flixbus)

    1. Take the bus from Niagara Falls USA to Ithacabus bus FlixBus 2685 / ...
    2. Take the bus from Ithaca to Bostonbus bus FlixBus 2691
    14h 26m
    $87–148

Niagara Falls to Lexington by bus (Greyhound)

Calendar7Weekly Buses
Duration14h 6mAverage Duration
Ticket$74Cheapest Price
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Questions & Answers

Map of how to get from Niagara Falls to Lexington.ExpandLaunch map view
  • Distance: 443.4 mi
  • Duration: 4h 39m

What companies run services between Niagara Falls, ON, Canada and Lexington, MA, USA?

Greyhound USA operates a bus from Buffalo to Boston once daily. Tickets cost $70–140 and the journey takes 10h 5m. Alternatively, you can take a train from Niagara Falls Amtrak Station to Massachusetts Ave @ Lexington Post Office via Buffalo Depew Station, Boston, South Station, Alewife, and Alewife in around 14h 14m.

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