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How to get fromNiagara Falls to Carlisleby bus (Greyhound), train (Amtrak), car, bus, plane, train, or bus (Flixbus)

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There are 6 ways to get from Niagara Falls to Carlisle by bus (Greyhound), train (Amtrak), car, bus, plane, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via State College

    best
    1. Take the bus from Buffalo to DuBoisbus bus
    2. Take the bus from DuBois to State Collegebus bus
    3. Take the bus from State College Bus Station to Harrisburg Bus Stationbus bus
    13h 33m
    $98–199

  2. Drive 287.5 mi

    cheapest
    1. Drive from Niagara Falls to Carlislecar car 287.5 mi
    6h 42m
    $53–76

  3. Train (Amtrak)

    1. Take the train from Niagara Falls Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Harrisburgtrain train Keystone Service / ...
    15h 6m
    $209–437

  4. Bus, fly, train

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Philadelphia International Airport (PHL)plane plane BUF - PHL
    3. Take the train from 30th Street Station to Harrisburgtrain train
    8h 39m
    $124–633

  5. Bus

    1. Take the bus from Buffalo to DuBoisbus bus
    2. Take the bus from DuBois to State Collegebus bus
    3. Take the bus from State College Regional Airport to Harrisburg Bus Stationbus bus
    13h 38m
    $105–204

  6. Bus #2

    1. Take the bus from Buffalo to Scranton Bus Stationbus bus Greyhound US0215 / ...
    2. Take the bus from Scranton, Pa to Harrisburg, Pabus bus 771
    13h 43m
    $67–164

Niagara Falls to Carlisle by bus and foot

Calendar7Weekly Services
Duration13h 33mAverage Duration
Ticket$98Cheapest Price
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Questions & Answers

Map of how to get from Niagara Falls to Carlisle.ExpandLaunch map view
  • Distance: 376.4 mi
  • Duration: 13h 33m

What companies run services between Niagara Falls, NY, USA and Carlisle, PA, USA?

You can take a bus from Pine Avenue & Main Street to Hanover St & High St via Buffalo, DuBois, State College, State College Bus Station, Harrisburg Bus Station, and Market Square Transfer Center in around 13h 33m. Alternatively, you can take a train from Niagara Falls Amtrak Station to N Hanover St & Louther St WB via Ny Moynihan Train Hall At Penn Station, Harrisburg, and Market Square Transfer Center in around 15h 6m.

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