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How to get fromNiagara Falls to Florence Stationby bus, plane, bus (Flixbus, Greyhound), train (Amtrak), or car

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There are 6 ways to get from Niagara Falls to Florence Station by bus, plane, bus (Flixbus, Greyhound), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Florence Regional Airport (FLO)plane plane BUF - FLO
    5h 54m
    $110–570

  2. Bus via Raleigh

    1. Take the bus from Niagara Falls USA to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    23h 8m
    $161–296

  3. Train (Amtrak)

    1. Take the train from Niagara Falls Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Florence Stationtrain train Palmetto / ...
    24h 34m
    $348–725

  4. Drive 744.2 mi

    1. Drive from Niagara Falls to Florence Stationcar car 744.2 mi
    15h 15m
    $136–197

  5. Bus

    1. Take the bus from Buffalo to New Yorkbus bus Adt N813 / ...
    2. Take the bus from New York, NY to Florence, SCbus bus Nyc
    23h 26m
    $163–432

  6. Train via Canadian Border (Amtrak)

    1. Take the train from Canadian Border to Ny Moynihan Train Hall At Penn Stationtrain train Maple Leaf
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Florence Stationtrain train Palmetto / ...
    26h 20m
    $348–725

Niagara Falls to Florence Station by train (Amtrak)

Calendar14Weekly Trains
Duration24h 34mAverage Duration
Ticket$348Cheapest Price
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Questions & Answers

Map of how to get from Niagara Falls to Florence Station.ExpandLaunch map view
  • Distance: 639.8 mi
  • Duration: 5h 54m

What companies run services between Niagara Falls, NY, USA and Florence Station, SC, USA?

You can take a bus from Niagara Falls USA to Florence Station via Newark Penn Station, Raleigh Bus Station, and Florence Bus Station in around 23h 8m. Alternatively, you can take a train from Niagara Falls Amtrak Station to Florence Station via Ny Moynihan Train Hall At Penn Station in around 24h 34m.

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