There are 7 ways to get from Niagara Falls to Florida Keys by bus, plane, train, car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Buffalo Niagara International Airport, fly to Key West International Airport
best- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW)plane BUF - EYW
9h 43m$172–541Bus to Toronto Pearson International Airport, fly to Key West International Airport
cheapest- Take the bus from Bus Terminal to Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floorbus
- Fly from Toronto Pearson International Airport (YYZ) to Key West International Airport (EYW)plane YYZ - EYW
12h 41m$164–530Bus, train via Newark
- Take the bus from Niagara Falls USA to Newark Penn Stationbus
- Take the train from Newark Penn Station to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
43h 54m$859–1,360Drive 1,541 mi
- Drive from Niagara Falls to Florida Keyscar 1,541 mi
26h 35m$282–407Bus to Buffalo Niagara International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Fort Lauderdale–Hollywood International Airport (FLL)plane BUF - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
10h 57m$287–761Train, bus
- Take the train from Niagara Falls Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
44h 40m$1,050–1,657Bus, train
- Take the bus from Buffalo, Ny to Pittsburgh, Pabus 530
- Take the train from Pittsburgh Amtrak Station to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
2d 5h$945–1,685
Niagara Falls to Florida Keys by bus, train, taxi, and foot
Comparing Your Travel Options
The cheapest way to get from Niagara Falls to Florida Keys is to bus and fly which costs $160 - $550 and takes 12h 41m.
The fastest way to get from Niagara Falls to Florida Keys is to bus and fly which takes 9h 43m and costs $170 - $550.
The distance between Niagara Falls and Florida Keys is 1342 miles. The road distance is 1550 miles.
The best way to get from Niagara Falls to Florida Keys without a car is to bus and train via Newark which takes 43h 54m and costs $850 - $1,400.
It takes approximately 9h 43m to get from Niagara Falls to Florida Keys, including transfers.
Yes, the driving distance between Niagara Falls to Florida Keys is 1550 miles. It takes approximately 26h 35m to drive from Niagara Falls to Florida Keys.
There are 969+ hotels available in Florida Keys.
What companies run services between Niagara Falls, NY, USA and Florida Keys, FL, USA?
There is no direct connection from Niagara Falls to Florida Keys. However, you can take the bus to Buffalo Niagara International Airport, walk to Buffalo Niagara International Airport (BUF) airport, fly to Key West International Airport (EYW), walk to Key West Airport, take the shuttle to Key West, FL, walk to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take a bus from Niagara Falls USA to Florida Keys via Newark, Penn Station, Newark Penn Station, Miami Amtrak Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 43h 54m.
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 55m
- When
- Every day
- Estimated price
- $95–460
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Atlanta
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $120–600
Flights from Toronto Pearson International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $80–390
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Key West International Airport via Reagan Washington
- Ave. Duration
- 5h 39m
- When
- Saturday
- Estimated price
- $95–450
Flights from Buffalo Niagara International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 6h 35m
- When
- Every day
- Estimated price
- $90–440
Flights from Buffalo Niagara International Airport to Key West International Airport via Miami
- Ave. Duration
- 8h 3m
- When
- Saturday
- Estimated price
- $95–450
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Charlotte
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $110–550
Flights from Toronto Pearson International Airport to Key West International Airport via Miami
- Ave. Duration
- 7h 7m
- When
- Tuesday, Friday, and Sunday
- Estimated price
- $80–700
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 15m
- When
- Saturday
- Estimated price
- $110–550
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Orlando
- Ave. Duration
- 4h 45m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $110–600
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Baltimore
- Ave. Duration
- 4h 51m
- When
- Tuesday, Wednesday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $110–600
- Website
- united.com
Flights from Buffalo Niagara International Airport to Key West International Airport via Washington Dulles
- Ave. Duration
- 6h 7m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $95–450
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport via Washington Dulles
- Ave. Duration
- 5h 3m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 2m
- When
- Every day
- Estimated price
- $110–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Newark Penn Station to Miami Amtrak Station
- Ave. Duration
- 28h 6m
- Frequency
- Once daily
- Estimated price
- $750–1,200
- Website
- Amtrak
Train from Niagara Falls Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 8h 53m
- Frequency
- 3 times a day
- Estimated price
- $250–400
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Station
- Ave. Duration
- 28h 29m
- Frequency
- Once daily
- Estimated price
- $750–1,200
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Miami Amtrak Station
- Ave. Duration
- 36h 44m
- Frequency
- Once daily
- Estimated price
- $850–1,400
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Niagara Falls USA to Buffalo Niagara International Airport
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $4–8
- Schedules at
- Flixbus USA
Bus from Niagara Falls USA to Newark Penn Station
- Ave. Duration
- 8h 30m
- Frequency
- 4 times a day
- Estimated price
- $65–100
- Schedules at
- Flixbus USA
Bus from Niagara Falls USA to Buffalo Niagara International Airport
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $4–8
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- Keys Shuttle
- Phone
- +1 866 488 4452
- [email protected]
- Website
- Megabus
Bus from Bus Terminal to Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- $7–55
- Website
- Megabus
- Adult Advanced Booking
- $7–45
- Adult Standard
- $16–55
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Buffalo, Ny to Pittsburgh, Pa
- Saver
- $50–210
- Flexible
- $90–220
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