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How to get fromNiagara Falls to Florida Keysby bus, plane, train, car, shuttle, or ferry

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There are 8 ways to get from Niagara Falls to Florida Keys by bus, plane, train, car, shuttle, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Buffalo Niagara International Airport, fly to Key West International Airport

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW)plane plane BUF - EYW
    9h 45m
    $212–702

  2. Train to Toronto Pearson International Airport, fly to Key West International Airport

    cheapest
    1. Take the train from Niagara Falls to Toronto Union Stationtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Key West International Airport (EYW)plane plane YYZ - EYW
    12h 41m
    $184–634

  3. Bus, train via Newark

    1. Take the bus from Niagara Falls USA to Newark Penn Stationbus bus
    2. Take the train from Newark Penn Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    43h 54m
    $555–1,075

  4. Drive 1,541 mi

    1. Drive from Niagara Falls to Florida Keyscar car 1,541 mi
    26h 35m
    $282–407

  5. Bus to Buffalo Niagara International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane BUF - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 48m
    $327–912

  6. Bus to Buffalo Niagara International Airport, fly to Ft. Myers, ferry

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Ft. Myers (RSW)plane plane BUF - RSW
    3. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    13h 22m
    $321–888

  7. Train, bus

    1. Take the train from Niagara Falls Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    44h 40m
    $643–1,270

  8. Bus, train

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the train from Pittsburgh Amtrak Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    2d 5h
    $592–1,390

Niagara Falls to Florida Keys by bus, train, taxi, and foot

Calendar7Weekly Services
Duration43h 54mAverage Duration
Ticket$555Cheapest Price
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Questions & Answers

Map of how to get from Niagara Falls to Florida Keys.ExpandLaunch map view
  • Distance: 1,334 mi
  • Duration: 9h 45m

What companies run services between Niagara Falls, NY, USA and Florida Keys, FL, USA?

There is no direct connection from Niagara Falls to Florida Keys. However, you can take the bus to Buffalo Niagara International Airport, walk to Buffalo Niagara International Airport (BUF) airport, fly to Key West International Airport (EYW), walk to Key West Airport, take the shuttle to Key West, FL, walk to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take a bus from Niagara Falls USA to Florida Keys via Newark, Penn Station, Newark Penn Station, Miami Amtrak Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 43h 54m.

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