There are 8 ways to get from Niagara Falls to Great Lakes by bus, plane, train (Amtrak), bus (Greyhound), car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Buffalo Niagara International Airport, fly to Chicago O'Hare International Airport
best- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane BUF - ORD
4h 28m$177–312Bus (Greyhound)
cheapest- Take the bus from Buffalo to Cleveland Bus Stationbus Greyhound US0171 / ...
- Take the bus from Cleveland Bus Station to Chicago Bus Stationbus Greyhound US0164
14h 6m$85–140Train
- Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain Maple Leaf / ...
- Take the train from Buffalo Depew Station to Chicago Union Stationtrain Lake Shore Limited
12h 31m$142–454Drive 517.4 mi
- Drive from Niagara Falls to Chicagocar 517.4 mi
8h 44m$95–137Bus to Toronto Pearson International Airport, fly to Windsor Airport, drive
- Take the bus from Bus Terminal to Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floorbus
- Fly from Toronto Pearson International Airport (YYZ) to Windsor Airport (YQG)plane YYZ - YQG
- Drive from Windsor-Airport-YQG to Algonac, MIcar
6h 5m$239–724Bus to Toronto Island Airport, fly to Chicago O'Hare International Airport
- Take the bus from Bus Terminal to Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floorbus
- Fly from Toronto Island Airport (YTZ) to Chicago O'Hare International Airport (ORD)plane YTZ - ORD
7h 2m$189–1,461Bus to Toronto Pearson International Airport, fly to Chicago O'Hare International Airport
- Take the bus from Bus Terminal to Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floorbus
- Fly from Toronto Pearson International Airport (YYZ) to Chicago O'Hare International Airport (ORD)plane YYZ - ORD
7h 22m$399–1,011Bus via Detroit
- Take the bus from Bus Terminal to Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floorbus
- Take the bus from Toronto to Detroit Bus Stationbus
- Take the bus from Detroit Bus Station to Chicagobus
18h 6m$94–191
Niagara Falls to Great Lakes by train and bus
Comparing Your Travel Options
The cheapest way to get from Niagara Falls to Great Lakes is to bus which costs $85 - $140 and takes 14h 6m.
The fastest way to get from Niagara Falls to Great Lakes is to bus and fly which takes 4h 28m and costs $170 - $320.
No, there is no direct bus from Niagara Falls to Great Lakes. However, there are services departing from Pine Avenue & Main Street and arriving at Congress Plaza & Michigan via Buffalo, Cleveland Bus Station and Jefferson & Harrison. The journey, including transfers, takes approximately 14h 6m.
No, there is no direct train from Niagara Falls station to Great Lakes station. However, there are services departing from Niagara Falls Amtrak Station and arriving at Chicago Union Station via Buffalo Depew Station. The journey, including transfers, takes approximately 12h 31m.
The distance between Niagara Falls and Great Lakes is 524 miles. The road distance is 520.4 miles.
The best way to get from Niagara Falls to Great Lakes without a car is to train which takes 12h 31m and costs $140 - $460.
It takes approximately 4h 28m to get from Niagara Falls to Great Lakes, including transfers.
Niagara Falls to Great Lakes bus services, operated by Greyhound USA, depart from Buffalo station.
Niagara Falls to Great Lakes train services, operated by Amtrak, depart from Niagara Falls Amtrak Station.
The best way to get from Niagara Falls to Great Lakes is to train which takes 12h 31m and costs $140 - $460. Alternatively, you can bus, which costs $85 - $140 and takes 14h 6m.
What companies run services between Niagara Falls, NY, USA and Great Lakes, MI, USA?
You can take a train from Niagara Falls Amtrak Station to Jackson & Wabash via Buffalo Depew Station, Chicago Union Station, and Jackson & Canal in around 12h 31m. Alternatively, you can take a bus from Pine Avenue & Main Street to Congress Plaza & Michigan via Ellicott Street & MTC Static, Buffalo, Cleveland Bus Station, Chicago Bus Station, and Jefferson & Harrison in around 14h 6m.
- Website
- aircanada.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $45–290
Flights from Toronto Pearson International Airport to Windsor Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $50–390
Flights from Toronto Island Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $40–260
Flights from Toronto Island Airport to Chicago O'Hare International Airport via Ottawa
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $60–320
Flights from Toronto Island Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $60–330
Flights from Toronto Pearson International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $35–240
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Niagara Falls Amtrak Station to Buffalo Depew Station
- Ave. Duration
- 46 min
- Frequency
- 3 times a day
- Estimated price
- $8–20
- Website
- Amtrak
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $130–310
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Niagara Falls USA to Buffalo Niagara International Airport
- Ave. Duration
- 55 min
- Frequency
- 5 times a day
- Estimated price
- $4–7
- Schedules at
- Flixbus USA
Bus from Toronto to Detroit Bus Station
- Ave. Duration
- 6h 50m
- Frequency
- 4 times a day
- Estimated price
- $35–55
- Schedules at
- Flixbus USA
Bus from Detroit Bus Station to Chicago
- Ave. Duration
- 6h 45m
- Frequency
- Once daily
- Estimated price
- $50–75
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
Niagara Falls to Great Lakes bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Niagara Falls to Great Lakes train services, operated by Amtrak, arrive at Buffalo Depew Station.
Yes, the driving distance between Niagara Falls to Great Lakes is 520 miles. It takes approximately 8h 44m to drive from Niagara Falls to Great Lakes.
There are 64+ hotels available in Great Lakes.






