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How to get fromNiagara Falls to Indianapolisby bus, plane, train, bus (Flixbus), car, bus (Greyhound), or train (Amtrak)

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There are 9 ways to get from Niagara Falls to Indianapolis by bus, plane, train, bus (Flixbus), car, bus (Greyhound), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Buffalo Niagara International Airport, fly

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Indianapolis (IND)plane plane BUF - IND
    6h 21m
    $97–559

  2. Bus via Brook Park (Greyhound)

    cheapest
    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Dayton Trotwood Bus Stationbus bus
    3. Take the bus from Dayton Trotwood Bus Station to Indianapolis Union Stationbus bus
    14h 27m
    $78–134

  3. Train, bus

    1. Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain train
    2. Take the train from Buffalo Depew Station to Toledotrain train
    3. Take the bus from Toledo to Indianapolis, INbus bus
    12h 25m
    $105–376

  4. Bus (Flixbus)

    1. Take the bus from Buffalo to Columbusbus bus FlixBus 2526
    2. Take the bus from Columbus to Indianapolisbus bus FlixBus 2511 / ...
    12h 57m
    $79–122

  5. Drive  511.4 mi

    1. Drive from Niagara Falls to Indianapoliscar car 511.4 mi
    9h
    $94–135

  6. Bus to Toronto Pearson International Airport, fly

    1. Take the bus from Bus Terminal to Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floorbus bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Indianapolis (IND)plane plane YYZ - IND
    7h 24m
    $319–1,055

  7. Train to Rochester, fly

    1. Take the train from Niagara Falls Amtrak Station to Rochestertrain train
    2. Fly from Rochester (ROC) to Indianapolis (IND)plane plane ROC - IND
    7h 30m
    $166–887

  8. Bus to Toronto Island Airport, fly

    1. Take the bus from Bus Terminal to Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floorbus bus
    2. Fly from Toronto Island Airport (YTZ) to Indianapolis (IND)plane plane YTZ - IND
    9h 30m
    $509–1,455

  9. Train

    1. Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain train
    2. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    18h 13m
    $189–571

Niagara Falls to Indianapolis by train and bus

Calendar14Weekly Services
Duration12h 25mAverage Duration
Ticket$105Cheapest Price
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Comparing Your Travel Options

Map of how to get from Niagara Falls to Indianapolis.ExpandLaunch map view
  • Distance: 497 mi
  • Duration: 6h 21m

What companies run services between Niagara Falls, NY, USA and Indianapolis, IN, USA?

You can take a bus from Pine Avenue & Main Street to Indianapolis via Ellicott Street & MTC Static, Buffalo, and Columbus in around 12h 57m. Alternatively, you can take a train from Niagara Falls Amtrak Station to Indianapolis via Buffalo Depew Station and Chicago Union Station in around 18h 13m.

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