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How to get fromNiagara Falls to Indianapolisby bus, plane, train, bus (Greyhound), car, bus (Flixbus), or train (Amtrak)

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There are 9 ways to get from Niagara Falls to Indianapolis by bus, plane, train, bus (Greyhound), car, bus (Flixbus), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Buffalo Niagara International Airport, fly

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Indianapolis (IND)plane plane BUF - IND
    6h 21m
    $117–710

  2. Bus

    cheapest
    1. Take the bus from Buffalo, NY to N Wilson Rd & Ferrell Pl - Columbusbus bus Buffalo
    2. Take the bus from Wilson & Ferrell Shell Station - Columbus to Indianapolis Union Stationbus bus Greyhound US0421
    14h 12m
    $64–142

  3. Train, bus

    1. Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain train
    2. Take the train from Buffalo Depew Station to Toledotrain train
    3. Take the bus from Toledo to Indianapolis, INbus bus
    12h 25m
    $125–409

  4. Drive 512.3 mi

    1. Drive from Niagara Falls to Indianapoliscar car 512.3 mi
    9h 3m
    $94–136

  5. Train to Toronto Pearson International Airport, fly

    1. Take the train from Niagara Falls to Toronto Union Stationtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Indianapolis (IND)plane plane YYZ - IND
    7h 25m
    $424–1,162

  6. Train to Rochester, fly

    1. Take the train from Niagara Falls Amtrak Station to Rochestertrain train
    2. Fly from Rochester (ROC) to Indianapolis (IND)plane plane ROC - IND
    7h 34m
    $166–840

  7. Train to Toronto Island Airport, fly

    1. Take the train from Canadian Border to Torontotrain train
    2. Fly from Toronto Island Airport (YTZ) to Indianapolis (IND)plane plane YTZ - IND
    9h 28m
    $629–1,456

  8. Bus via Pittsburgh

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the bus from Pittsburgh Intermodal Station to Indianapolisbus bus FlixBus N2642 / ...
    17h 47m
    $107–317

  9. Train

    1. Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain train
    2. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    18h 13m
    $239–624

Niagara Falls to Indianapolis by train and bus

Calendar7Weekly Services
Duration12h 25mAverage Duration
Ticket$125Cheapest Price
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Questions & Answers

Map of how to get from Niagara Falls to Indianapolis.ExpandLaunch map view
  • Distance: 497 mi
  • Duration: 6h 21m

What companies run services between Niagara Falls, NY, USA and Indianapolis, IN, USA?

You can take a bus from Pine Avenue & Main Street to Indianapolis Union Station via Buffalo, NY and Wilson & Ferrell Shell Station - Columbus in around 14h 12m. Alternatively, you can take a train from Niagara Falls Amtrak Station to Indianapolis via Buffalo Depew Station and Chicago Union Station in around 18h 13m.

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