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How to get fromNiagara Falls to Louisvilleby bus, plane, train, car, bus (Greyhound), or bus (Flixbus)

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There are 9 ways to get from Niagara Falls to Louisville by bus, plane, train, car, bus (Greyhound), or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Buffalo Niagara International Airport, fly to Louisville International Airport

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Louisville International Airport (SDF)plane plane BUF - SDF
    6h 51m
    $140–730

  2. Bus

    cheapest
    1. Take the bus from Buffalo, NY to Cincinnati, OHbus bus Buffalo
    2. Take the bus from Cincinnati Bus Station to Louisville Bus Stationbus bus Greyhound US0135 / ...
    15h 2m
    $64–187

  3. Bus via Akron

    1. Take the bus from Buffalo to Akronbus bus Bsb 11
    2. Take the bus from Akron to Louisvillebus bus Bsb 27
    14h 2m
    $142–207

  4. Train, bus

    1. Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain train
    2. Take the train from Buffalo Depew Station to Toledotrain train
    3. Take the bus from Toledo Bus Stop to Louisville Bus Stationbus bus
    14h 10m
    $174–454

  5. Drive 550.9 mi

    1. Drive from Niagara Falls to Louisvillecar car 550.9 mi
    9h 25m
    $101–146

  6. Bus to Buffalo Niagara International Airport, fly to Blue Grass Airport, drive

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Blue Grass Airport (LEX)plane plane BUF - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    6h 53m
    $212–1,046

  7. Train to Rochester, fly to Louisville International Airport

    1. Take the train from Niagara Falls Amtrak Station to Rochestertrain train
    2. Fly from Rochester (ROC) to Louisville International Airport (SDF)plane plane ROC - SDF
    7h 41m
    $415–791

  8. Train to Toronto Pearson International Airport, fly to Louisville International Airport

    1. Take the train from Niagara Falls to Toronto Union Stationtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Louisville International Airport (SDF)plane plane YYZ - SDF
    9h 52m
    $98–593

  9. Bus via Cincinnati

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the bus from Pittsburgh Intermodal Station to Cincinnatibus bus
    3. Take the bus from Cincinnati to Louisvillebus bus
    20h 12m
    $112–360

Niagara Falls to Louisville by bus

Calendar7Weekly Buses
Duration14h 2mAverage Duration
Ticket$142Cheapest Price
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Questions & Answers

Map of how to get from Niagara Falls to Louisville.ExpandLaunch map view
  • Distance: 530.1 mi
  • Duration: 6h 51m

What companies run services between Niagara Falls, NY, USA and Louisville, KY, USA?

You can take a bus from Pine Avenue & Main Street to Louisville via Buffalo and Akron in around 14h 2m.

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