There are 11 ways to get from Niagara Falls to Millsboro by bus, plane, shuttle, train, bus (Flixbus), car, subway, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Buffalo Niagara International Airport, fly to Philadelphia International Airport, shuttle
best- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Philadelphia International Airport (PHL)plane BUF - PHL
- Take a shuttle bus from Philadelphia Airport to Lewes Transit Center
8h 8m$133–473Drive 461.1 mi
cheapest- Drive from Niagara Falls to Millsborocar 461.1 mi
9h 28m$85–122Train, bus
- Take the train from Niagara Falls Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Wilmingtontrain
- Take the bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rdbus 305
15h 36m$290–1,054Bus
- Take the bus from Niagara Falls USA to New York Midtownbus
- Take the bus from Midtown - 400 8th Ave to Wilmington, DE - 3 W 4th St.bus
- Take the bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rdbus 305
16h 56m$102–151Bus to Buffalo Niagara International Airport, fly to Baltimore-Washington International Airport, train, bus
- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Baltimore-Washington International Airport (BWI)plane BUF - BWI
- Take the train from BWI Thurgood Marshall to Wilmingtontrain
- Take the bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rdbus
9h 21m$85–989Bus to Buffalo Niagara International Airport, fly to Ronald Reagan Washington National Airport, train, bus
- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Ronald Reagan Washington National Airport (DCA)plane BUF - DCA
- Take the train from Washington Union Station to Wilmingtontrain
- Take the bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rdbus
9h 49m$115–1,174Bus to Toronto Pearson International Airport, fly to Philadelphia International Airport, shuttle
- Take the bus from Bus Terminal to Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floorbus
- Fly from Toronto Pearson International Airport (YYZ) to Philadelphia International Airport (PHL)plane YYZ - PHL
- Take a shuttle bus from Philadelphia Airport to Lewes Transit Center
11h 6m$680–2,232Bus to Buffalo Niagara International Airport, fly to John F. Kennedy International Airport, train, bus
- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to John F. Kennedy International Airport (JFK)plane BUF - JFK
- Take the train from Ny Moynihan Train Hall At Penn Station to Wilmingtontrain
- Take the bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rdbus
10h 39m$92–956Bus to Buffalo Niagara International Airport, fly to Washington Dulles International Airport, subway, train, bus
- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Washington Dulles International Airport (IAD)plane BUF - IAD
- Take the subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platformsubway
- Take the train from Washington Union Station to Wilmingtontrain
- Take the bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rdbus
10h 22m$95–1,063Train, bus via Canadian Border
- Take the train from Canadian Border to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Wilmingtontrain
- Take the bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rdbus 305
17h 22m$290–1,054Bus via Ellicott Street & MTC Static
- Take the bus from Buffalo to Port Authority Bus Terminalbus
- Take the bus from Port Authority Bus Terminal to Wilmington Bus Stationbus
- Take the bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rdbus 305
17h 52m$93–307
Niagara Falls to Millsboro by train and bus
Comparing Your Travel Options
The cheapest way to get from Niagara Falls to Millsboro is to drive which costs $80 - $130 and takes 9h 28m.
The fastest way to get from Niagara Falls to Millsboro is to bus and fly and shuttle which takes 8h 8m and costs $130 - $480.
No, there is no direct bus from Niagara Falls to Millsboro. However, there are services departing from Niagara Falls USA and arriving at Monroe St At Brandywine Village Apts via Midtown - 400 8th Ave, Wilmington Tc and Rehoboth P-N-R @ Country Club Rd. The journey, including transfers, takes approximately 16h 56m.
The distance between Niagara Falls and Millsboro is 441 miles. The road distance is 463.8 miles.
The best way to get from Niagara Falls to Millsboro without a car is to train and bus which takes 15h 36m and costs $290 - $1,100.
It takes approximately 8h 8m to get from Niagara Falls to Millsboro, including transfers.
Niagara Falls to Millsboro bus services, operated by Flixbus USA, depart from Niagara Falls USA station.
Niagara Falls to Millsboro bus services, operated by Flixbus USA, arrive at New York Midtown station.
Yes, the driving distance between Niagara Falls to Millsboro is 464 miles. It takes approximately 9h 28m to drive from Niagara Falls to Millsboro.
There are 1249+ hotels available in Millsboro.
What companies run services between Niagara Falls, NY, USA and Millsboro, DE, USA?
You can take a bus from Niagara Falls USA to Monroe St At Brandywine Village Apts via New York Midtown, Midtown - 400 8th Ave, Wilmington, DE - 3 W 4th St., Wilmington Tc, and Rehoboth P-N-R @ Country Club Rd in around 16h 56m.
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Baltimore-Washington International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $55–370
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Philadelphia International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $55–390
Flights from Buffalo Niagara International Airport to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $75–500
Flights from Toronto Pearson International Airport to Philadelphia International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $50–340
Flights from Toronto Pearson International Airport to Philadelphia International Airport via Ronald Reagan Washington National Airport
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $60–370
- Website
- united.com
Flights from Buffalo Niagara International Airport to Philadelphia International Airport via Washington Dulles International Airport
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- $65–430
Flights from Toronto Pearson International Airport to Philadelphia International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $50–340
Flights from Toronto Pearson International Airport to Philadelphia International Airport via Washington Dulles International Airport
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $60–370
Flights from Buffalo Niagara International Airport to Washington Dulles International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $55–390
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to John F. Kennedy International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $40–270
- Website
- delta.com
Flights from Buffalo Niagara International Airport to John F. Kennedy International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $40–270
- Website
- aircanada.com
Flights from Toronto Pearson International Airport to Philadelphia International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $50–340
Flights from Toronto Pearson International Airport to Philadelphia International Airport via Montreal
- Ave. Duration
- 4h 2m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–420
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Niagara Falls Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 8h 53m
- Frequency
- 3 times a day
- Estimated price
- $250–400
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Wilmington
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- $60–100
- Website
- Amtrak
Train from BWI Thurgood Marshall to Wilmington
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- $40–70
- Website
- Amtrak
Train from Washington Union Station to Wilmington
- Ave. Duration
- 1h 21m
- Frequency
- Hourly
- Estimated price
- $55–95
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Wilmington
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- $60–100
- Website
- Amtrak
Train from Washington Union Station to Wilmington
- Ave. Duration
- 1h 21m
- Frequency
- Hourly
- Estimated price
- $55–95
- Website
- Amtrak
Train from Canadian Border to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 10h 39m
- Frequency
- Once daily
- Estimated price
- $250–400
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Wilmington
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- $60–100
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Wilmington
- Ave. Duration
- 1h 35m
- Frequency
- Every 2 hours
- Estimated price
- $26–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $26–460
- First Class
- $140–650
Train from BWI Thurgood Marshall to Wilmington
- Ave. Duration
- 56 min
- Frequency
- 3 times a day
- Estimated price
- $18–600
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $18–450
- First Class
- $120–600
Train from Washington Union Station to Wilmington
- Ave. Duration
- 1h 16m
- Frequency
- Every 3 hours
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
Train from Ny Moynihan Train Hall At Penn Station to Wilmington
- Ave. Duration
- 1h 35m
- Frequency
- Every 2 hours
- Estimated price
- $26–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $26–460
- First Class
- $140–650
Train from Washington Union Station to Wilmington
- Ave. Duration
- 1h 16m
- Frequency
- Every 3 hours
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
Train from Ny Moynihan Train Hall At Penn Station to Wilmington
- Ave. Duration
- 1h 35m
- Frequency
- Every 2 hours
- Estimated price
- $26–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $26–460
- First Class
- $140–650
Subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platform
- Ave. Duration
- 50 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–3
- Website
- Washington Metropolitan Area Transit Authority
- standard fare after 9:30 p.m
- $2–3
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Niagara Falls USA to Buffalo Niagara International Airport
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $4–8
- Schedules at
- Flixbus USA
Bus from Niagara Falls USA to New York Midtown
- Ave. Duration
- 9h 5m
- Frequency
- Every 4 hours
- Estimated price
- $65–110
- Schedules at
- Flixbus USA
Bus from Niagara Falls USA to Buffalo Niagara International Airport
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $4–8
- Schedules at
- Flixbus USA
Bus from Niagara Falls USA to Buffalo Niagara International Airport
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $4–8
- Schedules at
- Flixbus USA
Bus from Niagara Falls USA to Buffalo Niagara International Airport
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $4–8
- Schedules at
- Flixbus USA
Bus from Niagara Falls USA to Buffalo Niagara International Airport
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- $4–8
- Schedules at
- Flixbus USA
- Phone
- +1 302-470-6784
- [email protected]
- Website
- Lewes Bus
Shuttle from Philadelphia Airport to Lewes Transit Center
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- $70
- Schedules at
- Lewes Bus
Shuttle from Philadelphia Airport to Lewes Transit Center
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- $70
- Schedules at
- Lewes Bus
- Phone
- +1 800-652-3278
- Website
- DART
Bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rd
- Ave. Duration
- 2h 2m
- Frequency
- Twice daily
- Estimated price
- $5–7
- Website
- DART
Bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rd
- Ave. Duration
- 2h 2m
- Frequency
- Twice daily
- Estimated price
- $5–7
- Website
- DART
Bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rd
- Ave. Duration
- 2h 2m
- Frequency
- Twice daily
- Estimated price
- $5–7
- Website
- DART
Bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rd
- Ave. Duration
- 2h 2m
- Frequency
- Twice daily
- Estimated price
- $5–7
- Website
- DART
Bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rd
- Ave. Duration
- 2h 2m
- Frequency
- Twice daily
- Estimated price
- $5–7
- Website
- DART
Bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rd
- Ave. Duration
- 2h 2m
- Frequency
- Twice daily
- Estimated price
- $5–7
- Website
- DART
Bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rd
- Ave. Duration
- 2h 2m
- Frequency
- Twice daily
- Estimated price
- $5–7
- Website
- DART
Bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rd
- Ave. Duration
- 2h 2m
- Frequency
- Twice daily
- Estimated price
- $5–7
- Website
- DART
- [email protected]
- Website
- Rockledge Bus
Bus from Midtown - 400 8th Ave to Wilmington, DE - 3 W 4th St.
- Ave. Duration
- 2h 20m
- Frequency
- 5 times a day
- Estimated price
- $27–40
- Website
- Rockledge Bus
- Phone
- +1 866 488 4452
- [email protected]
- Website
- Megabus
Bus from Bus Terminal to Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- $7–55
- Website
- Megabus
- Adult Advanced Booking
- $7–45
- Adult Standard
- $16–55
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Buffalo to Port Authority Bus Terminal
- Ave. Duration
- 8h 5m
- Frequency
- 5 times a day
- Estimated price
- $70–110
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Wilmington Bus Station
- Ave. Duration
- 2h 20m
- Frequency
- 4 times a day
- Estimated price
- $29–45
- Website
- Greyhound
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Buffalo to Port Authority Bus Terminal
- Ave. Duration
- 8h 30m
- Frequency
- 3 times a day
- Estimated price
- $55–250
- Website
- Trailways
- Schedules at
- Trailways
- Saver
- $55–240
- Flexible
- $100–250
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