Rome2Rio

How to get fromNiagara Falls to Mississippiby bus, plane, train (Amtrak), bus (Greyhound, Flixbus), car, or train

Find Transport to Mississippi

See all options

There are 7 ways to get from Niagara Falls to Mississippi by bus, plane, train (Amtrak), bus (Greyhound, Flixbus), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Memphis

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Memphis (MEM)plane plane BUF - MEM
    6h 6m
    $187–934

  2. Bus, fly to Gulfport-Biloxi Regional Airport

    cheapest
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Gulfport-Biloxi Regional Airport (GPT)plane plane BUF - GPT
    7h 47m
    $126–621

  3. Train

    1. Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain train
    2. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Jacksontrain train
    28h 54m
    $699–1,241

  4. Bus

    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Jacksonbus bus
    28h 57m
    $177–307

  5. Drive  1,111.2 mi

    1. Drive from Niagara Falls to Jacksoncar car 1,111.2 mi
    19h 36m
    $203–293

  6. Bus, fly to Jackson/Vicksburg

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Jackson/Vicksburg (JAN)plane plane BUF - JAN
    7h 5m
    $135–527

  7. Bus, train

    1. Take the bus from Bus Terminal to Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floorbus bus
    2. Take the bus from Toronto to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Chicagobus bus
    4. Take the train from Homewood to Jacksontrain train
    35h 22m
    $484–845

Niagara Falls to Mississippi by train

Calendar7Weekly Trains
Duration28h 54mAverage Duration
Ticket$699Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Niagara Falls to Mississippi.ExpandLaunch map view
  • Distance: 850.8 mi
  • Duration: 6h 6m

What companies run services between Niagara Falls, NY, USA and Mississippi, USA?

You can take a train from Niagara Falls Amtrak Station to Jackson via Buffalo Depew Station and Chicago Union Station in around 28h 54m. Alternatively, you can take a bus from Pine Avenue & Main Street to Jackson via Ellicott Street & MTC Static, Buffalo, Cleveland Bus Station, Nashville Bus Station, and Memphis Bus Station in around 28h 57m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There