Rome2Rio

How to get fromNiagara Falls to Port Saint Lucieby bus, plane, bus (Greyhound, Flixbus), train, or car

Find Transport to Port Saint Lucie

See all options

There are 10 ways to get from Niagara Falls to Port Saint Lucie by bus, plane, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Buffalo Niagara International Airport, fly to Fort Lauderdale–Hollywood International Airport, bus

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane BUF - FLL
    3. Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus bus
    8h 30m
    $215–653

  2. Train to Toronto Pearson International Airport, fly to President Donald J. Trump International Airport, bus

    cheapest
    1. Take the train from Niagara Falls to Toronto Union Stationtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to President Donald J. Trump International Airport (PBI)plane plane YYZ - PBI
    3. Take the bus from WPB ITC at BAY D to GATLIN BLVD at I-95 P/R LOTbus bus
    12h 13m
    $131–658

  3. Bus

    1. Take the bus from Buffalo, NY to Youngstown, OHbus bus
    2. Take the bus from Youngstown Bus Stop to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Port St Luciebus bus
    35h 36m
    $225–427

  4. Train, bus

    1. Take the train from Niagara Falls Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Kissimmee Amtrak Stationtrain train
    3. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    36h 36m
    $553–1,098

  5. Drive 1,287 mi

    1. Drive from Niagara Falls to Port Saint Luciecar car 1,287 mi
    21h 45m
    $235–340

  6. Bus to Buffalo Niagara International Airport, fly to Orlando, bus

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Orlando (MCO)plane plane BUF - MCO
    3. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    8h 58m
    $179–352

  7. Train to Toronto Pearson International Airport, fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Take the train from Niagara Falls to Toronto Union Stationtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane YYZ - FLL
    3. Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus bus
    11h 26m
    $162–806

  8. Train to Toronto Pearson International Airport, fly to Orlando, bus

    1. Take the train from Niagara Falls to Toronto Union Stationtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Orlando (MCO)plane plane YYZ - MCO
    3. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    11h 54m
    $206–905

  9. Bus to Buffalo Niagara International Airport, fly to Tampa, train, bus

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Tampa (TPA)plane plane BUF - TPA
    3. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    4. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    11h 45m
    $237–706

  10. Bus, train

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the train from Pittsburgh Amtrak Station to Kissimmee Amtrak Stationtrain train
    3. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    43h 20m
    $484–1,114

Niagara Falls to Port Saint Lucie by bus

Calendar7Weekly Buses
Duration35h 36mAverage Duration
Ticket$225Cheapest Price
See schedules

Questions & Answers

Map of how to get from Niagara Falls to Port Saint Lucie.ExpandLaunch map view
  • Distance: 1,296.6 mi
  • Duration: 8h 30m

What companies run services between Niagara Falls, NY, USA and Port Saint Lucie, FL, USA?

You can take a bus from Pine Avenue & Main Street to SW PSL Blvd & SE Bayshore Blvd via Buffalo, NY, Youngstown, OH, Youngstown Bus Stop, Washington Union Station, Orlando Bus Station, and SW Gatlin Blvd & SW Brescia St in around 35h 36m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers