Rome2Rio

How to get fromNiagara Falls to San Diegoby bus, plane, train (Amtrak), bus (Greyhound, Amtrak), car, or train

Find Transport to San Diego

See all options

There are 6 ways to get from Niagara Falls to San Diego by bus, plane, train (Amtrak), bus (Greyhound, Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Buffalo Niagara International Airport, fly

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to San Diego International Airport (SAN)plane plane BUF - SAN
    8h 35m
    $255–1,008

  2. Train

    1. Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain train
    2. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    4. Take the train from Fullerton Amtrak Station to San Diegotrain train
    2d 11h
    $909–2,064

  3. Bus

    1. Take the bus from Buffalo, NY to Columbus - Mound Stbus bus
    2. Take the bus from Columbus to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles to San Diegobus bus
    2d 16h
    $427–827

  4. Drive 2,580.5 mi

    1. Drive from Niagara Falls to San Diegocar car 2,580.5 mi
    40h 59m
    $471–681

  5. Train to Toronto Pearson International Airport, fly

    1. Take the train from Niagara Falls to Toronto Union Stationtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to San Diego International Airport (SAN)plane plane YYZ - SAN
    9h 50m
    $312–1,361

  6. Bus, train

    1. Take the bus from Niagara Falls, ON to Toronto Union Stationbus bus
    2. Take the bus from Toronto to Detroit Bus Stationbus bus
    3. Take the bus from Detroit to Chicago Union Stationbus bus
    4. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    5. Take the train from Fullerton Amtrak Station to San Diegotrain train
    2d 16h
    $872–1,834

Niagara Falls to San Diego by train

Calendar7Weekly Trains
Duration2d 11hAverage Duration
Ticket$909Cheapest Price
See schedules

Questions & Answers

Map of how to get from Niagara Falls to San Diego.ExpandLaunch map view
  • Distance: 2,223.7 mi
  • Duration: 8h 35m

What companies run services between Niagara Falls, NY, USA and San Diego, CA, USA?

You can take a train from Niagara Falls Amtrak Station to San Diego via Buffalo Depew Station, Chicago Union Station, and Fullerton Amtrak Station in around 2d 11h. Alternatively, you can take a bus from Pine Avenue & Main Street to San Diego via Buffalo, NY, Columbus, St Louis Bus Station, Los Angeles Union Station, and Los Angeles in around 2d 16h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers