There are 6 ways to get from Niagara Falls to South Boston by bus (Greyhound), train (Amtrak), car, bus, plane, train, bus (Flixbus), or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Buffalo to Bostonbus Greyhound US0171
12h 7m$77–122Train
- Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain Maple Leaf / ...
- Take the train from Buffalo Depew Station to Bostontrain Lake Shore Limited
13h 13m$129–450Drive 468 mi
- Drive from Niagara Falls to South Bostoncar 468 mi
8h 14m$86–124Bus, fly to Laguardia Airport, train
- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA)plane BUF - LGA
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
8h 21m$133–633Bus via Ithaca (Flixbus)
- Take the bus from Niagara Falls USA to Ithacabus FlixBus 2685 / ...
- Take the bus from Ithaca to Bostonbus FlixBus 2691
13h 25m$83–132Bus, fly to Provincetown Municipal Airport, ferry
- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Provincetown Municipal Airport (PVC)plane BUF - PVC
- Take the ferry from MacMillan Pier, Provincetown, MA to World Trade Center Pier, Boston, MAferry
8h 12m$156–527
Niagara Falls to South Boston by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Niagara Falls to South Boston is to bus which costs $75 - $130 and takes 12h 7m.
The fastest way to get from Niagara Falls to South Boston is to bus and fly and ferry which takes 8h 12m and costs $150 - $550.
No, there is no direct bus from Niagara Falls to South Boston. However, there are services departing from Pine Avenue & Main Street and arriving at Boston via Buffalo. The journey, including transfers, takes approximately 12h 7m.
No, there is no direct train from Niagara Falls station to South Boston. However, there are services departing from Niagara Falls Amtrak Station and arriving at Boston via Buffalo Depew Station. The journey, including transfers, takes approximately 13h 13m.
The distance between Niagara Falls and South Boston is 496 miles. The road distance is 470.8 miles.
The best way to get from Niagara Falls to South Boston without a car is to bus which takes 12h 7m and costs $75 - $130.
It takes approximately 12h 7m to get from Niagara Falls to South Boston, including transfers.
Niagara Falls to South Boston bus services, operated by Greyhound USA, depart from Buffalo station.
Niagara Falls to South Boston train services, operated by Amtrak, depart from Niagara Falls Amtrak Station.
The best way to get from Niagara Falls to South Boston is to bus which takes 12h 7m and costs $75 - $130. Alternatively, you can train, which costs $120 - $450 and takes 13h 13m.
What companies run services between Niagara Falls, NY, USA and South Boston, MA, USA?
Greyhound USA operates a bus from Buffalo to Boston once daily. Tickets cost $75–120 and the journey takes 10h 5m. Alternatively, you can take a train from Niagara Falls Amtrak Station to Boston via Buffalo Depew Station in around 13h 13m.
- Website
- capeair.com
Flights from Buffalo Niagara International Airport to Provincetown Municipal Airport via Boston
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $65–410
Flights from Buffalo Niagara International Airport to Provincetown Municipal Airport via Laguardia Airport, Boston
- Ave. Duration
- 6h 23m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–430
Flights from Buffalo Niagara International Airport to Provincetown Municipal Airport via Newark, Boston
- Ave. Duration
- 6h 26m
- When
- Every day
- Estimated price
- $70–430
Flights from Buffalo Niagara International Airport to Provincetown Municipal Airport via New York JFK, Boston
- Ave. Duration
- 6h 12m
- When
- Every day
- Estimated price
- $75–440
Flights from Buffalo Niagara International Airport to Provincetown Municipal Airport via Reagan Washington, Boston
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $90–480
Flights from Buffalo Niagara International Airport to Provincetown Municipal Airport via Baltimore, Boston
- Ave. Duration
- 6h 40m
- When
- Sunday, Tuesday, and Wednesday
- Estimated price
- $85–470
Flights from Buffalo Niagara International Airport to Provincetown Municipal Airport via Washington Dulles, Boston
- Ave. Duration
- 6h 30m
- When
- Monday and Sunday
- Estimated price
- $90–480
Flights from Buffalo Niagara International Airport to Provincetown Municipal Airport via Philadelphia, Boston
- Ave. Duration
- 6h 57m
- When
- Monday to Saturday
- Estimated price
- $80–450
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Niagara Falls Amtrak Station to Buffalo Depew Station
- Ave. Duration
- 46 min
- Frequency
- 3 times a day
- Estimated price
- $8–21
- Website
- Amtrak
Train from Buffalo Depew Station to Boston
- Ave. Duration
- 11h 27m
- Frequency
- Once daily
- Estimated price
- $120–310
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 14m
- Frequency
- Every 3 hours
- Estimated price
- $55–150
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Buffalo to Boston
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Greyhound
- Phone
- +1 617-748-1428
- Website
- Provincetown Fast Ferry
Ferry from MacMillan Pier, Provincetown, MA to World Trade Center Pier, Boston, MA
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- $87
- Website
- Provincetown Fast Ferry
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Booking & Getting There
Niagara Falls to South Boston bus services, operated by Greyhound USA, arrive at Boston station.
Niagara Falls to South Boston train services, operated by Amtrak, arrive at Buffalo Depew Station.
Yes, the driving distance between Niagara Falls to South Boston is 471 miles. It takes approximately 8h 14m to drive from Niagara Falls to South Boston.
Book your Niagara Falls to South Boston train tickets online with Omio.
Book your Niagara Falls to South Boston bus tickets online with Omio.
There are 1743+ hotels available in South Boston.








