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How to get fromNiagara Falls to Winston-Salemby bus, plane, bus (Greyhound), train, car, or train (Amtrak)

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There are 9 ways to get from Niagara Falls to Winston-Salem by bus, plane, bus (Greyhound), train, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Buffalo Niagara International Airport, fly to Piedmont Triad International Airport

    best
    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Piedmont Triad International Airport (GSO)plane plane BUF - GSO
    6h 36m
    $164–831

  2. Bus

    cheapest
    1. Take the bus from Buffalo, NY to Robert K Pfaff Transit Center - Akronbus bus
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Charleston, WVbus bus
    3. Take the bus from Charleston Bus Station to Winston Salem(Trans Center)bus bus
    17h 27m
    $80–202

  3. Train, bus

    1. Take the train from Niagara Falls Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    21h 48m
    $315–652

  4. Drive 621.3 mi

    1. Drive from Niagara Falls to Winston-Salemcar car 621.3 mi
    10h 52m
    $114–164

  5. Bus to Buffalo Niagara International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane plane BUF - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    7h 1m
    $146–804

  6. Bus to Buffalo Niagara International Airport, fly to Raleigh-Durham International Airport, bus

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Raleigh-Durham International Airport (RDU)plane plane BUF - RDU
    3. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    7h 39m
    $143–488

  7. Train to Rochester, fly to Charlotte Douglas International Airport, bus

    1. Take the train from Niagara Falls Amtrak Station to Rochestertrain train
    2. Fly from Rochester (ROC) to Charlotte Douglas International Airport (CLT)plane plane ROC - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    8h 3m
    $185–984

  8. Bus via Charleston

    1. Take the bus from Buffalo to Akronbus bus
    2. Take the bus from Akron to Charlestonbus bus
    3. Take the bus from Charleston Bus Station to Winston Salem(Trans Center)bus bus
    17h 27m

  9. Train (Amtrak)

    1. Take the train from Canadian Border to Ny Moynihan Train Hall At Penn Stationtrain train Maple Leaf
    2. Take the train from Ny Moynihan Train Hall At Penn Station to High Pointtrain train Crescent / ...
    24h 11m
    $323–658

Niagara Falls to Winston-Salem by bus

Calendar7Weekly Buses
Duration17h 27mAverage Duration
Ticket$80Cheapest Price
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Questions & Answers

Map of how to get from Niagara Falls to Winston-Salem.ExpandLaunch map view
  • Distance: 530.6 mi
  • Duration: 6h 36m

What companies run services between Niagara Falls, NY, USA and Winston-Salem, NC, USA?

You can take a bus from Pine Avenue & Main Street to Winston Salem(Trans Center) via Buffalo, NY, Robert K Pfaff Transit Center - Akron, and Charleston Bus Station in around 17h 27m. Alternatively, you can take a train from Canadian Border to Winston-Salem Transportation Center via Ny Moynihan Train Hall At Penn Station, High Point, and High Point Terminal in around 24h 11m.

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