There are 10 ways to get from Niagara Falls to Wytheville by bus, train, car, plane, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Buffalo, NY to Robert K Pfaff Transit Center - Akronbus
- Take the bus from Robert K Pfaff Transit Center - Akron to Charleston, WVbus
- Take the bus from Charleston, WV to Wythevillebus
15h 16m$81–210Train, bus
- Take the train from Niagara Falls Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Roanoketrain
- Take the bus from Roanoke Bus Stop to Max Meadowsbus
21h 54m$336–673Drive 538.6 mi
- Drive from Niagara Falls to Wythevillecar 538.6 mi
9h 21m$99–142Bus to Buffalo Niagara International Airport, fly to Roanoke Regional Airport-Woodrum Field, bus
- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Roanoke Regional Airport-Woodrum Field (ROA)plane BUF - ROA
- Take the bus from Airport to Exit 118 - Park and Ridebus
- Take the bus from Christiansburg to Wytheville Rural King Parking Lotbus
9h 29m$107–495Bus via Washington
- Take the bus from Niagara Falls USA to Ithacabus
- Take the bus from Ithaca to Washington Union Stationbus
- Take the bus from Washington Union Station to Wytheville Rural King Parking Lotbus
23h 20m$160–255Bus to Buffalo Niagara International Airport, fly to Charlotte Douglas International Airport, bus
- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane BUF - CLT
- Take the bus from Charlotte Bus Station to Max Meadowsbus
7h 51m$194–849Bus to Buffalo Niagara International Airport, fly to Washington Dulles International Airport, bus
- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Washington Dulles International Airport (IAD)plane BUF - IAD
- Take the bus from Dulles International Airport to Wytheville Rural King Parking Lotbus
9h 43m$105–473Train to Rochester, fly to Charlotte Douglas International Airport, bus
- Take the train from Niagara Falls Amtrak Station to Rochestertrain
- Fly from Rochester (ROC) to Charlotte Douglas International Airport (CLT)plane ROC - CLT
- Take the bus from Charlotte Bus Station to Max Meadowsbus
8h 53m$234–1,029Bus to Buffalo Niagara International Airport, fly to Raleigh-Durham International Airport, bus
- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Raleigh-Durham International Airport (RDU)plane BUF - RDU
- Take the bus from Durham to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Wythevillebus
10h 5m$173–525Train to Toronto Pearson International Airport, fly to Charlotte Douglas International Airport, bus
- Take the train from Niagara Falls to Toronto Union Stationtrain
- Fly from Toronto Pearson International Airport (YYZ) to Charlotte Douglas International Airport (CLT)plane YYZ - CLT
- Take the bus from Charlotte Bus Station to Max Meadowsbus
10h 40m$581–1,552
Niagara Falls to Wytheville by bus
Questions & Answers
The cheapest way to get from Niagara Falls to Wytheville is to drive which costs $95 - $150 and takes 9h 21m.
The fastest way to get from Niagara Falls to Wytheville is to bus and fly which takes 7h 51m and costs $190 - $850.
No, there is no direct bus from Niagara Falls to Wytheville. However, there are services departing from Pine Avenue & Main Street and arriving at Wytheville via Buffalo, NY, Robert K Pfaff Transit Center - Akron and Charleston, WV. The journey, including transfers, takes approximately 15h 16m.
The distance between Niagara Falls and Wytheville is 621 miles. The road distance is 541.8 miles.
The best way to get from Niagara Falls to Wytheville without a car is to bus which takes 15h 16m and costs $80 - $210.
It takes approximately 15h 16m to get from Niagara Falls to Wytheville, including transfers.
Niagara Falls to Wytheville bus services, operated by Flixbus USA, depart from Niagara Falls USA station.
Niagara Falls to Wytheville bus services, operated by Flixbus USA, arrive at Ithaca station.
Yes, the driving distance between Niagara Falls to Wytheville is 542 miles. It takes approximately 9h 21m to drive from Niagara Falls to Wytheville.
Book your Niagara Falls to Wytheville bus tickets online with Omio.
What companies run services between Niagara Falls, NY, USA and Wytheville, VA, USA?
You can take a bus from Pine Avenue & Main Street to Wytheville via Buffalo, NY, Robert K Pfaff Transit Center - Akron, Charleston, WV, and Wytheville in around 15h 16m.
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Roanoke Regional Airport-Woodrum Field via Charlotte Douglas International Airport
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $100–550
Flights from Buffalo Niagara International Airport to Roanoke Regional Airport-Woodrum Field via Philadelphia
- Ave. Duration
- 6h 49m
- When
- Every day
- Estimated price
- $90–490
Flights from Buffalo Niagara International Airport to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 6h 44m
- When
- Every day
- Estimated price
- $130–600
Flights from Buffalo Niagara International Airport to Roanoke Regional Airport-Woodrum Field via New York La Guardia
- Ave. Duration
- 7h 32m
- When
- Every day
- Estimated price
- $100–550
Flights from Buffalo Niagara International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $130–750
Flights from Buffalo Niagara International Airport to Charlotte Douglas International Airport via Philadelphia
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $150–800
Flights from Rochester to Charlotte Douglas International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $130–750
Flights from Rochester to Charlotte Douglas International Airport via Reagan Washington
- Ave. Duration
- 4h 2m
- When
- Sunday
- Estimated price
- $140–750
Flights from Buffalo Niagara International Airport to Raleigh-Durham International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $110–600
Flights from Buffalo Niagara International Airport to Raleigh-Durham International Airport via Philadelphia
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $100–600
Flights from Toronto Pearson International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- $90–480
Flights from Toronto Pearson International Airport to Charlotte Douglas International Airport via Reagan Washington
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $95–550
- Website
- united.com
Flights from Buffalo Niagara International Airport to Roanoke Regional Airport-Woodrum Field via Washington Dulles International Airport
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $80–460
Flights from Buffalo Niagara International Airport to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 6h 47m
- When
- Every day
- Estimated price
- $130–600
Flights from Buffalo Niagara International Airport to Charlotte Douglas International Airport via Washington Dulles International Airport
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $130–750
Flights from Buffalo Niagara International Airport to Washington Dulles International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $60–410
Flights from Rochester to Charlotte Douglas International Airport via Washington Dulles International Airport
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $130–750
Flights from Buffalo Niagara International Airport to Raleigh-Durham International Airport via Washington Dulles International Airport
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $95–550
Flights from Toronto Pearson International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $90–480
Flights from Toronto Pearson International Airport to Charlotte Douglas International Airport via Washington Dulles International Airport
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $95–500
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Charlotte Douglas International Airport via Baltimore
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $140–750
Flights from Buffalo Niagara International Airport to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 4h 15m
- When
- Saturday
- Estimated price
- $180–900
Flights from Rochester to Charlotte Douglas International Airport via Baltimore
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $140–750
Flights from Buffalo Niagara International Airport to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $100–550
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Roanoke Regional Airport-Woodrum Field via Atlanta
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $130–650
Flights from Buffalo Niagara International Airport to Roanoke Regional Airport-Woodrum Field via New York La Guardia
- Ave. Duration
- 4h 50m
- When
- Saturday
- Estimated price
- $100–550
Flights from Buffalo Niagara International Airport to Charlotte Douglas International Airport via Detroit
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $150–800
Flights from Rochester to Charlotte Douglas International Airport via Detroit
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $160–800
- Website
- aircanada.com
Flights from Toronto Pearson International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $90–480
Flights from Toronto Pearson International Airport to Charlotte Douglas International Airport via Washington Dulles International Airport
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $95–500
- Website
- flyfrontier.com
Flights from Buffalo Niagara International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 40m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $120–420
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Niagara Falls Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 8h 53m
- Frequency
- 3 times a day
- Estimated price
- $150–310
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Roanoke
- Ave. Duration
- 9h 33m
- Frequency
- Once daily
- Estimated price
- $140–300
- Website
- https://www.amtrak.com/home.html
Train from Niagara Falls Amtrak Station to Rochester
- Ave. Duration
- 1h 41m
- Frequency
- 3 times a day
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888 842-7245
- Website
- viarail.ca
Train from Niagara Falls Amtrak Station to Rochester
- Ave. Duration
- 1h 41m
- Frequency
- Once daily
- Estimated price
- $25–170
- Website
- https://www.viarail.ca/en
- Escape
- $25–80
- Business
- $55–160
- Business Plus
- $65–170
- Economy
- $28–90
- Economy Plus
- $30–95
Train from Niagara Falls to Toronto Union Station
- Ave. Duration
- 1h 58m
- Frequency
- Once daily
- Estimated price
- $22–170
- Website
- https://www.viarail.ca/en
- Escape
- $22–75
- Business
- $55–150
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $27–90
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Buffalo, NY to Robert K Pfaff Transit Center - Akron
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $22–65
- Website
- https://baronsbus.com
Bus from Robert K Pfaff Transit Center - Akron to Charleston, WV
- Ave. Duration
- 4h 35m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- https://baronsbus.com
Bus from Charleston, WV to Wytheville
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $13–50
- Website
- https://baronsbus.com
Bus from Winston Salem(Trans Center) to Wytheville
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $7–40
- Website
- https://baronsbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Roanoke Bus Stop to Max Meadows
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $9–18
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Max Meadows
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Max Meadows
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
Bus from Durham to Winston Salem(Trans Center)
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- $12–23
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Max Meadows
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Niagara Falls USA to Buffalo Niagara International Airport
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- $5–9
- Schedules at
- flixbus.com
Bus from Niagara Falls USA to Ithaca
- Ave. Duration
- 4h 25m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Schedules at
- flixbus.com
Bus from Ithaca to Washington Union Station
- Ave. Duration
- 10h
- Frequency
- 5 times a week
- Estimated price
- $85–150
- Schedules at
- flixbus.com
Bus from Niagara Falls USA to Buffalo Niagara International Airport
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- $5–9
- Schedules at
- flixbus.com
Bus from Niagara Falls USA to Buffalo Niagara International Airport
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- $5–9
- Schedules at
- flixbus.com
Bus from Niagara Falls USA to Buffalo Niagara International Airport
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- $5–9
- Schedules at
- flixbus.com
- Phone
- +1 540 982 2222
- [email protected]
- Website
- valleymetro.com
Bus from Airport to Exit 118 - Park and Ride
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- $4–5
- Website
- https://www.valleymetro.com
- Phone
- +1-800-827-3490
- [email protected]
- Website
- virginiabreeze.drpt.virginia.gov
Bus from Christiansburg to Wytheville Rural King Parking Lot
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $18–22
- Schedules at
- virginiabreeze.drpt.virginia.gov
Bus from Washington Union Station to Wytheville Rural King Parking Lot
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Estimated price
- $45–55
- Schedules at
- virginiabreeze.drpt.virginia.gov
Bus from Dulles International Airport to Wytheville Rural King Parking Lot
- Ave. Duration
- 5h 35m
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- virginiabreeze.drpt.virginia.gov
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