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How to get fromNiceville to Knoxvilleby plane, bus (Greyhound, Flixbus), car, bus (Flixbus, Greyhound), bus, or train

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There are 8 ways to get from Niceville to Knoxville by plane, bus (Greyhound, Flixbus), car, bus (Flixbus, Greyhound), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Destin–Fort Walton Beach Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Mcghee Tyson Airport (TYS)plane plane VPS - TYS
    1h 49m
    $174–693

  2. Drive 495.5 mi

    cheapest
    1. Drive from Niceville to Knoxvillecar car 495.5 mi
    8h 28m
    $91–131

  3. Bus via Jacksonville

    1. Take the bus from Crestview to Tallahasseebus bus
    2. Take the bus from Tallahassee to Jacksonvillebus bus
    3. Take the bus from Jacksonville to New York City Chinatownbus bus
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    40h 25m
    $423–612

  4. Drive to Northwest Florida Beaches International Airport, fly

    1. Drive from Niceville to Northwest Florida Beaches International Airport (ECP)car car
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Mcghee Tyson Airport (TYS)plane plane ECP - TYS
    4h 26m
    $160–684

  5. Drive to Pensacola International Airport, fly

    1. Drive from Niceville to Pensacola-Airport-PNScar car
    2. Fly from Pensacola International Airport (PNS) to Mcghee Tyson Airport (TYS)plane plane PNS - TYS
    4h 36m
    $156–636

  6. Bus

    1. Take the bus from Crestview to Tallahasseebus bus
    2. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to New York Midtownbus bus
    4. Take the bus from New York to Knoxvillebus bus Nyc
    42h 26m
    $480–720

  7. Bus #2

    1. Take the bus from Crestview to Tallahasseebus bus
    2. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Port Authority Bus Terminalbus bus
    4. Take the bus from New York to Knoxvillebus bus Nyc
    44h 2m
    $470–750

  8. Bus, train

    1. Take the bus from Crestview to Wildwoodbus bus
    2. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    3. Take the train from Jacksonville to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York to Knoxvillebus bus Nyc
    44h 33m
    $663–1,128

Destin–Fort Walton Beach Airport (VPS) to Mcghee Tyson Airport (TYS) flights

Calendar22Weekly Planes
Duration2h 35mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

Map of how to get from Niceville to Knoxville.ExpandLaunch map view
  • Distance: 413.7 mi
  • Duration: 1h 49m

What companies run services between Niceville, FL, USA and Knoxville, TN, USA?

Allegiant Air, Delta, and Southwest Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Mcghee Tyson Airport (TYS) 3 times a day. Alternatively, you can take a vehicle from Niceville to Knoxville via Crestview, Tallahassee, N Monroe Street and Silver Slipper Lane, Tallahassee, Jacksonville, New York, NY, and Knoxville, TN in around 40h 25m.

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