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How to get fromNijmegen to Mainzby train, bus, car, or plane

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There are 7 ways to get from Nijmegen to Mainz by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Arnhem Centraal to Frankfurt(M) Flughafen Fernbftrain train Ice / ...
    3h 49m
    €41–144

  2. Bus

    cheapest
    1. Take the bus from Nijmegen Centraal Station to Essen central train stationbus bus 037
    2. Take the bus from Essen central train station to Wiesbaden central train stationbus bus FlixBus 027
    7h 34m
    €32–53

  3. Drive  321 km

    1. Drive from Nijmegen to Mainzcar car 321 km
    3h 7m
    €59–86

  4. Train to Düsseldorf International Airport, fly

    1. Take the train from Arnhem Centraal to Duesseldorf Hbftrain train
    2. Fly from Düsseldorf International Airport (DUS) to Frankfurt (FRA)plane plane DUS - FRA
    4h 24m
    €115–226

  5. Train via Düsseldorf

    1. Take the train from Nijmegen to Venlotrain train
    2. Take the train from Venlo to Duesseldorf Hbftrain train
    3. Take the train from Düsseldorf Hbf to Mainz, Hauptbahnhoftrain train 91 / ...
    5h 5m
    €41–114

  6. Train via Cologne

    1. Take the train from Kleve Bahnhof to Düsseldorf Hbftrain train
    2. Take the train from Duesseldorf Hbf to Koeln Messe/Deutztrain train Re
    3. Take the train from Köln Messe/Deutz Bf to Mainz, Hauptbahnhoftrain train
    7h 13m
    €55–167

  7. Train to Amsterdam Airport Schiphol, fly

    1. Take the train from Nijmegen to Schiphol Airport Train Stationtrain train
    2. Fly from Amsterdam Airport Schiphol (AMS) to Frankfurt (FRA)plane plane AMS - FRA
    5h 7m
    €127–336

Nijmegen to Mainz by train

Calendar213Weekly Trains
Duration3h 49mAverage Duration
Ticket€41Cheapest Price
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Comparing Your Travel Options

Map of how to get from Nijmegen to Mainz.ExpandLaunch map view
  • Distance: 375 km
  • Duration: 3h 49m

What companies run services between Nijmegen, Netherlands and Mainz, Germany?

Nederlandse Spoorwegen (NS) operates a train from Arnhem Centraal to Frankfurt(M) Flughafen Fernbf hourly. Tickets cost €35–75 and the journey takes 2h 38m. Deutsche Bahn Intercity (DB IC) also services this route every 4 hours. Alternatively, you can take a bus from Nijmegen Centraal Station to Wiesbaden-Mainz-Kastel Bahnhof via Essen central train station, Wiesbaden central train station, and Wiesbaden Hauptbahnhof in around 7h 34m.

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