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How to get fromNiles to Louisvilleby plane, bus (Greyhound, Amtrak), train, bus, car, subway, or bus (Amtrak)

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There are 7 ways to get from Niles to Louisville by plane, bus (Greyhound, Amtrak), train, bus, car, subway, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Louisville International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    4h 14m
    $70–430

  2. Bus via Indianapolis

    cheapest
    1. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus Greyhound US0100 / ...
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    9h 4m
    $54–105

  3. Train, bus (Amtrak)

    1. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    10h 15m
    $86–182

  4. Drive 307.3 mi

    1. Drive from Niles to Louisvillecar car 307.3 mi
    5h 21m
    $57–81

  5. Bus, subway, subway to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the bus from Harlem Station to Jefferson Park Transit Centerbus bus
    2. Take the subway from Jefferson Park to Clark/Lakesubway subway
    3. Take the subway from Clark/Lake to Midwaysubway subway
    4. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    4h 45m
    $87–565

  6. Fly Chicago O'Hare International Airport to Blue Grass Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 23m
    $117–676

  7. Bus (Amtrak)

    1. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    9h 31m
    $55–65

Niles to Louisville by bus and foot

Calendar14Weekly Services
Duration9h 4mAverage Duration
Ticket$54Cheapest Price
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Questions & Answers

Map of how to get from Niles to Louisville.ExpandLaunch map view
  • Distance: 304.2 mi
  • Duration: 4h 14m

What companies run services between Niles, IL, USA and Louisville, KY, USA?

American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF) every 3 hours. Alternatively, you can take a bus from Harlem Station to Louisville, KY via Jefferson Park Transit Center, Washington & Jefferson, Chicago Bus Station, and Indianapolis Union Station in around 9h 4m.

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