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How to get fromNiles to Panama City Beachby plane, bus (Greyhound, Amtrak), train, bus, car, subway, or bus (Flixbus, Greyhound)

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There are 10 ways to get from Niles to Panama City Beach by plane, bus (Greyhound, Amtrak), train, bus, car, subway, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Northwest Florida Beaches International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Northwest Florida Beaches International Airport (ECP)plane plane ORD - ECP
    4h 31m
    $129–472

  2. Fly Chicago O'Hare International Airport to Destin–Fort Walton Beach Airport, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Destin–Fort Walton Beach Airport (VPS)plane plane ORD - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    5h 23m
    $89–413

  3. Bus

    1. Take the bus from Chicago Train Station to Nashville Bus Stationbus bus
    2. Take the bus from Nashville Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    26h 38m
    $154–272

  4. Train, bus via New Orleans

    1. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train
    2. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    3. Take the bus from Mobile Bus Station to Panama City Beach Bus Stationbus bus
    29h 42m
    $347–754

  5. Drive 902.4 mi

    1. Drive from Niles to Panama City Beachcar car 902.4 mi
    17h 5m
    $165–238

  6. Bus, subway, subway to Chicago Midway International Airport, fly to Northwest Florida Beaches International Airport

    1. Take the bus from Harlem Station to Jefferson Park Transit Centerbus bus
    2. Take the subway from Jefferson Park to Clark/Lakesubway subway
    3. Take the subway from Clark/Lake to Midwaysubway subway
    4. Fly from Chicago Midway International Airport (MDW) to Northwest Florida Beaches International Airport (ECP)plane plane MDW - ECP
    4h 56m
    $146–557

  7. Fly Chicago Midway International Airport to Destin–Fort Walton Beach Airport, drive

    1. Fly from Chicago Midway International Airport (MDW) to Destin–Fort Walton Beach Airport (VPS)plane plane MDW - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    5h 59m
    $106–508

  8. Fly Chicago O'Hare International Airport to Pensacola International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Pensacola International Airport (PNS)plane plane ORD - PNS
    2. Take the bus from Pensacola Airport to Panama City Beach Bus Stationbus bus
    7h 25m
    $92–387

  9. Bus via Atlanta

    1. Take the bus from Chicago to Bloomingtonbus bus
    2. Take the bus from Bloomington to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    29h 8m
    $183–325

  10. Train, bus

    1. Take the train from Chicago Union Station to Jacksonvilletrain train Floridian
    2. Take the bus from Jacksonville to Panama City Beach Bus Stationbus bus Greyhound US0760S
    45h 47m
    $544–1,202

Chicago O'Hare International Airport (ORD) to Northwest Florida Beaches International Airport (ECP) flights

Calendar62Weekly Planes
Duration4h 12mAverage Duration
Ticket$77Cheapest Price
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Questions & Answers

Map of how to get from Niles to Panama City Beach.ExpandLaunch map view
  • Distance: 842.6 mi
  • Duration: 4h 31m

What companies run services between Niles, IL, USA and Panama City Beach, FL, USA?

American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Northwest Florida Beaches International Airport (ECP) every 3 hours. Alternatively, you can take a bus from Harlem Station to Panama City Beach via Jefferson Park Transit Center, Jackson & Austin Terminal, Jackson & Clinton, Chicago Train Station, Nashville Bus Station, Tallahassee, and Panama City Beach Bus Station in around 26h 38m.

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