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How to get fromNiles to St. Louisby bus, plane, train (Amtrak), bus (Flixbus), car, or subway

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There are 5 ways to get from Niles to St. Louis by bus, plane, train (Amtrak), bus (Flixbus), car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Chicago O'Hare International Airport, fly

    best
    1. Take the bus from Harlem Station to Jefferson Park Transit Centerbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    3h 29m
    $277–710

  2. Bus

    cheapest
    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    8h 29m
    $55–90

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    6h 42m
    $94–197

  4. Drive 300.3 mi

    1. Drive from Niles to St. Louiscar car 300.3 mi
    5h 4m
    $55–80

  5. Bus, subway, subway to Chicago Midway International Airport, fly

    1. Take the bus from Harlem Station to Jefferson Park Transit Centerbus bus
    2. Take the subway from Jefferson Park to Clark/Lakesubway subway
    3. Take the subway from Clark/Lake to Midwaysubway subway
    4. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    4h 16m
    $89–565

Niles to St. Louis by bus, subway, foot, and train (Amtrak)

Calendar38Weekly Services
Duration6h 42mAverage Duration
Ticket$94Cheapest Price
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Questions & Answers

Map of how to get from Niles to St. Louis.ExpandLaunch map view
  • Distance: 284.6 mi
  • Duration: 3h 29m

What companies run services between Niles, IL, USA and St. Louis, MO, USA?

Amtrak operates a train from Chicago Union Station to St. Louis 5 times a day. Tickets cost $90–190 and the journey takes 4h 46m. Alternatively, FlixBus-us operates a bus from Chicago Bus Station to St Louis Bus Station 3 times a day, and the journey takes 5h 55m. Flixbus USA also services this route twice daily.

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