Rome2Rio

How to get fromNogales to Santa Anaby bus, plane, train, car, shuttle, or bus (Flixbus)

Find Transport to Santa Ana

See all options

There are 9 ways to get from Nogales to Santa Ana by bus, plane, train, car, shuttle, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Tucson, fly to John Wayne Airport Orange County

    best
    1. Take the bus from Nogales, AZ to Tucsonbus bus
    2. Fly from Tucson (TUS) to John Wayne Airport Orange County (SNA)plane plane TUS - SNA
    5h 54m
    $117–527

  2. Drive 533 mi

    cheapest
    1. Drive from Nogales to Santa Anacar car 533 mi
    8h 38m
    $98–141

  3. Bus via Ontario

    1. Take the bus from Nogales, AZ to 285 S East End Ave - Pomonabus bus Nogales
    12h 41m
    $100–134

  4. Bus, train

    1. Take the bus from 219 N Arroyo Blvd - Nogales to 4207 S 6th Ave - Tucsonbus bus
    2. Take the train from Tucson Amtrak Station to Los Angelestrain train
    3. Take the train from Los Angeles to Santa Anatrain train
    14h 38m
    $215–407

  5. Shuttle to Phoenix, fly to John Wayne Airport Orange County

    1. Take a shuttle bus from Nogales to Sky Harbor International Airportshuttle bus
    2. Fly from Phoenix (PHX) to John Wayne Airport Orange County (SNA)plane plane PHX - SNA
    5h 54m
    $307–898

  6. Bus to Scottsdale Airport, fly to John Wayne Airport Orange County

    1. Take the bus from Nogales, AZ to Phoenixbus bus
    2. Fly from Scottsdale Airport (SCF) to John Wayne Airport Orange County (SNA)plane plane SCF - SNA
    7h 16m
    $143–502

  7. Bus to Tucson, fly to Los Angeles International Airport, train

    1. Take the bus from Nogales, AZ to Tucsonbus bus
    2. Fly from Tucson (TUS) to Los Angeles International Airport (LAX)plane plane TUS - LAX
    3. Take the train from Los Angeles to Santa Anatrain train
    8h 16m
    $526–1,158

  8. Bus to Tucson, fly to San Diego International Airport, train

    1. Take the bus from Nogales, AZ to Tucsonbus bus
    2. Fly from Tucson (TUS) to San Diego International Airport (SAN)plane plane TUS - SAN
    3. Take the train from San Diego to Santa Anatrain train
    8h 48m
    $479–892

  9. Bus

    1. Take the bus from Nogales to Huntington Parkbus bus Guadalajara
    2. Take the bus from Huntington Park to Santa Ana Bus Stopbus bus FlixBus 2017 / ...
    12h 45m
    $116–151

Nogales to Santa Ana by bus

Calendar42Weekly Buses
Duration12h 41mAverage Duration
Ticket$100Cheapest Price
See schedules

Questions & Answers

Map of how to get from Nogales to Santa Ana.ExpandLaunch map view
  • Distance: 499.5 mi
  • Duration: 5h 54m

What companies run services between Nogales, AZ, USA and Santa Ana, CA, USA?

Tufesa operates a bus from Nogales, AZ to 285 S East End Ave - Pomona every 4 hours. Tickets cost $95–120 and the journey takes 9h 10m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides