Rome2Rio

How to get fromNorth Carolina to Chicagoby plane, bus (Greyhound, Amtrak), car, bus, or train

Find Transport to Chicago

See all options

There are 10 ways to get from North Carolina to Chicago by plane, bus (Greyhound, Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Piedmont Triad International Airport to Chicago O'Hare International Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)plane plane GSO - ORD
    3h 7m
    $98–421

  2. Fly Charlotte Douglas International Airport to Chicago Midway International Airport

    cheapest
    1. Fly from Charlotte Douglas International Airport (CLT) to Chicago Midway International Airport (MDW)plane plane CLT - MDW
    4h 3m
    $74–397

  3. Bus

    1. Take the bus from Charlotte Bus Station to Toledo Bus Stopbus bus Greyhound US0140
    2. Take the bus from Toledo to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    19h 2m
    $161–250

  4. Drive  741.7 mi

    1. Drive from Charlotte to Chicagocar car 741.7 mi
    12h 54m
    $136–196

  5. Fly Wilmington International Airport to Chicago O'Hare International Airport

    1. Fly from Wilmington International Airport (ILM) to Chicago O'Hare International Airport (ORD)plane plane ILM - ORD
    3h 29m
    $76–342

  6. Fly Charlotte Douglas International Airport to Chicago O'Hare International Airport

    1. Fly from Charlotte Douglas International Airport (CLT) to Chicago O'Hare International Airport (ORD)plane plane CLT - ORD
    4h 23m
    $124–397

  7. Fly Raleigh-Durham International Airport to Chicago Midway International Airport

    1. Fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW)plane plane RDU - MDW
    4h 5m
    $154–228

  8. Fly Raleigh-Durham International Airport to Chicago O'Hare International Airport

    1. Fly from Raleigh-Durham International Airport (RDU) to Chicago O'Hare International Airport (ORD)plane plane RDU - ORD
    4h 40m
    $174–758

  9. Bus, train

    1. Take the bus from Charlotte Bus Station to Toledo Bus Stopbus bus Greyhound US0140
    2. Take the train from Toledo to Chicago Union Stationtrain train Floridian / ...
    19h 3m
    $156–290

  10. Bus via Columbus

    1. Take the bus from Charlotte to Columbusbus bus Bsb 33
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Chicagobus bus Columbus / ...
    19h 20m
    $79–180

North Carolina to Chicago by bus

Calendar2Weekly Buses
Duration19h 2mAverage Duration
Ticket$161Cheapest Price
See schedules

Questions & Answers

Map of how to get from North Carolina to Chicago.ExpandLaunch map view
  • Distance: 618.7 mi
  • Duration: 3h 7m

What companies run services between North Carolina, USA and Chicago, IL, USA?

American Airlines, United Airlines, and Delta fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD) hourly. Alternatively, you can take a bus from Charlotte Bus Station to Chicago Union Station via Toledo in around 19h 2m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers