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How to get fromNorth Carolina to Chicagoby plane, bus (Greyhound, Amtrak), car, bus, or train

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There are 10 ways to get from North Carolina to Chicago by plane, bus (Greyhound, Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Piedmont Triad International Airport to Chicago O'Hare International Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)plane plane GSO - ORD
    3h 14m
    $108–441

  2. Fly Wilmington International Airport to Chicago O'Hare International Airport

    cheapest
    1. Fly from Wilmington International Airport (ILM) to Chicago O'Hare International Airport (ORD)plane plane ILM - ORD
    3h 34m
    $76–342

  3. Bus

    1. Take the bus from Charlotte Bus Station to Toledo Bus Stopbus bus Greyhound US0140
    2. Take the bus from Toledo to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    18h 47m
    $185–315

  4. Drive 741.7 mi

    1. Drive from Charlotte to Chicagocar car 741.7 mi
    12h 54m
    $136–196

  5. Fly Charlotte Douglas International Airport to Chicago O'Hare International Airport

    1. Fly from Charlotte Douglas International Airport (CLT) to Chicago O'Hare International Airport (ORD)plane plane CLT - ORD
    4h 25m
    $134–417

  6. Fly Raleigh-Durham International Airport to Chicago Midway International Airport

    1. Fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW)plane plane RDU - MDW
    4h 5m
    $154–308

  7. Fly Charlotte Douglas International Airport to Chicago Midway International Airport

    1. Fly from Charlotte Douglas International Airport (CLT) to Chicago Midway International Airport (MDW)plane plane CLT - MDW
    4h 3m
    $84–437

  8. Fly Raleigh-Durham International Airport to Chicago O'Hare International Airport

    1. Fly from Raleigh-Durham International Airport (RDU) to Chicago O'Hare International Airport (ORD)plane plane RDU - ORD
    4h 42m
    $184–508

  9. Bus, train

    1. Take the bus from Charlotte Bus Station to Toledo Bus Stopbus bus Greyhound US0140
    2. Take the train from Toledo to Chicago Union Stationtrain train Floridian / ...
    18h 48m
    $175–345

  10. Bus via Columbus

    1. Take the bus from Charlotte to Columbusbus bus Bsb 33
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Chicagobus bus Columbus / ...
    19h 20m
    $145–268

North Carolina to Chicago by bus

Calendar2Weekly Buses
Duration18h 47mAverage Duration
Ticket$185Cheapest Price
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Questions & Answers

Map of how to get from North Carolina to Chicago.ExpandLaunch map view
  • Distance: 618.7 mi
  • Duration: 3h 14m

What companies run services between North Carolina, USA and Chicago, IL, USA?

American Airlines, United Airlines, and Delta fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD) hourly. Alternatively, you can take a bus from Charlotte Bus Station to Chicago Union Station via Toledo in around 18h 47m.

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