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How to get fromNorth Carolina to La Crosseby plane, bus, train, car, bus (Flixbus), or bus (Greyhound, Flixbus)

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There are 7 ways to get from North Carolina to La Crosse by plane, bus, train, car, bus (Flixbus), or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Piedmont Triad International Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to La Crosse (LSE)plane plane GSO - LSE
    5h 7m
    $160–609

  2. Fly from Raleigh-Durham International Airport

    cheapest
    1. Fly from Raleigh-Durham International Airport (RDU) to La Crosse (LSE)plane plane RDU - LSE
    6h 55m
    $116–496

  3. Bus, train

    1. Take the bus from Charlotte Bus Station to Toledo Bus Stopbus bus
    2. Take the train from Toledo to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train
    25h 2m
    $247–523

  4. Drive 1,023.1 mi

    1. Drive from Charlotte to La Crossecar car 1,023.1 mi
    17h 34m
    $187–270

  5. Fly from Charlotte Douglas International Airport

    1. Fly from Charlotte Douglas International Airport (CLT) to La Crosse (LSE)plane plane CLT - LSE
    6h 24m
    $121–575

  6. Bus via Columbus

    1. Take the bus from Charlotte Bus Station to Hurricanebus bus
    2. Take the bus from Hurricane to Columbus - Mound Stbus bus
    3. Take the bus from Columbus to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to La Crossebus bus
    27h 24m
    $168–327

  7. Bus

    1. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to La Crossebus bus
    28h 55m
    $200–381

North Carolina to La Crosse by bus and train

Calendar14Weekly Services
Duration25h 2mAverage Duration
Ticket$247Cheapest Price
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Questions & Answers

Map of how to get from North Carolina to La Crosse.ExpandLaunch map view
  • Distance: 822.9 mi
  • Duration: 5h 7m

What companies run services between North Carolina, USA and La Crosse, WI, USA?

American Airlines flies from Piedmont Triad International Airport (GSO) to La Crosse (LSE) every 4 hours. Alternatively, you can take a bus from Charlotte Bus Station to La Crosse via Hurricane, Columbus - Mound St, S Grant Ave & E Mound St, S High St & E Rich St, Columbus, Milwaukee Intermodal Station, and Milwaukee in around 27h 24m.

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