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How to get fromNorth Carolina to Louisvilleby plane, bus (Flixbus, Amtrak), car, or bus (Greyhound)

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There are 6 ways to get from North Carolina to Louisville by plane, bus (Flixbus, Amtrak), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Charlotte Douglas International Airport to Louisville International Airport

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF)plane plane CLT - SDF
    4h
    $93–605

  2. Drive 437.5 mi

    cheapest
    1. Drive from Charlotte to Louisvillecar car 437.5 mi
    9h 4m
    $80–116

  3. Bus via Atlanta

    1. Take the bus from Charlotte Bus Station to Atlanta Downtownbus bus
    2. Take the bus from Grand Hyatt Atlanta in Buckhead to Omni Nashville Hotelbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    14h 37m
    $217–283

  4. Fly Raleigh-Durham International Airport to Louisville International Airport

    1. Fly from Raleigh-Durham International Airport (RDU) to Louisville International Airport (SDF)plane plane RDU - SDF
    4h 16m
    $98–556

  5. Fly Charlotte Douglas International Airport to Blue Grass Airport, drive

    1. Fly from Charlotte Douglas International Airport (CLT) to Blue Grass Airport (LEX)plane plane CLT - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 11m
    $135–821

  6. Bus

    1. Take the bus from Charlotte Bus Station to Wilson & Ferrell Shell Station - Columbusbus bus Greyhound US0140
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Stationbus bus Cleveland
    15h 30m
    $93–197

North Carolina to Louisville by bus

Calendar7Weekly Buses
Duration15h 30mAverage Duration
Ticket$93Cheapest Price
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Questions & Answers

Map of how to get from North Carolina to Louisville.ExpandLaunch map view
  • Distance: 349.3 mi
  • Duration: 4h

What companies run services between North Carolina, USA and Louisville, KY, USA?

American Airlines flies from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF) 5 times a day. Alternatively, you can take a bus from Charlotte Bus Station to Louisville, KY via Atlanta Downtown, Civic Center Station, Arts Center Station, 15Th St Ne @ Arts Center Way Ne, Peachtree Rd @ Highland Dr, Grand Hyatt Atlanta in Buckhead, Omni Nashville Hotel, Peabody Station Outbound, Fulton Station Outbound, and Nashville in around 14h 37m.

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