Rome2Rio

How to get fromNorth Carolina to Saint Charlesby plane, bus (Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)

Find Transport to Saint Charles

See all options

There are 7 ways to get from North Carolina to Saint Charles by plane, bus (Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Charlotte Douglas International Airport

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)plane plane CLT - STL
    4h 29m
    $116–656

  2. Bus via Atlanta

    1. Take the bus from Charlotte Bus Station to Atlanta Downtownbus bus FlixBus N2470
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    18h 24m
    $131–242

  3. Drive 730 mi

    1. Drive from Charlotte to Saint Charlescar car 730 mi
    12h 30m
    $134–193

  4. Fly from Piedmont Triad International Airport

    1. Fly from Piedmont Triad International Airport (GSO) to Lambert–St. Louis International Airport (STL)plane plane GSO - STL
    5h 19m
    $165–790

  5. Fly from Wilmington International Airport

    1. Fly from Wilmington International Airport (ILM) to Lambert–St. Louis International Airport (STL)plane plane ILM - STL
    5h 35m
    $128–571

  6. Fly from Raleigh-Durham International Airport

    1. Fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL)plane plane RDU - STL
    4h 40m
    $556–1,006

  7. Bus

    1. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus Greyhound US0670 / ...
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    18h 45m
    $126–244

North Carolina to Saint Charles by bus, subway, and train

Calendar4Weekly Services
Duration18h 24mAverage Duration
Ticket$131Cheapest Price
See schedules

Questions & Answers

Map of how to get from North Carolina to Saint Charles.ExpandLaunch map view
  • Distance: 595.5 mi
  • Duration: 4h 29m

What companies run services between North Carolina, USA and Saint Charles, MO, USA?

American Airlines, Southwest Airlines, and Delta fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Charlotte Bus Station to 4375 Rider Trail North Sb via Atlanta Downtown, Civic Center Station, Garnett Station, Atlanta Bus Station, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, and North Hanley Transit Center in around 18h 24m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers