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How to get fromNorth Carolina to St. Louisby plane, bus (Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)

Find Transport to St. Louis

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There are 9 ways to get from North Carolina to St. Louis by plane, bus (Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Charlotte Douglas International Airport

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)plane plane CLT - STL
    4h 5m
    $100–555

  2. Bus via Atlanta

    1. Take the bus from Charlotte Bus Station to Atlanta Downtownbus bus FlixBus N2470
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    16h 59m
    $132–210

  3. Drive  709 mi

    1. Drive from Charlotte to St. Louiscar car 709 mi
    12h 6m
    $130–187

  4. Fly from Piedmont Triad International Airport

    1. Fly from Piedmont Triad International Airport (GSO) to Lambert–St. Louis International Airport (STL)plane plane GSO - STL
    5h 6m
    $144–689

  5. Fly from Fayetteville Municipal Airport

    1. Fly from Fayetteville Municipal Airport (FAY) to Lambert–St. Louis International Airport (STL)plane plane FAY - STL
    5h
    $114–572

  6. Fly from Wilmington International Airport

    1. Fly from Wilmington International Airport (ILM) to Lambert–St. Louis International Airport (STL)plane plane ILM - STL
    4h 58m
    $117–620

  7. Fly from Raleigh-Durham International Airport

    1. Fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL)plane plane RDU - STL
    4h 26m
    $106–606

  8. Bus

    1. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus Greyhound US0670 / ...
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    17h 5m
    $129–214

  9. Bus via Sandy Springs

    1. Take the bus from Charlotte to Atlantabus bus Charlotte
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    20h 33m
    $145–230

North Carolina to St. Louis by bus and subway

Calendar4Weekly Services
Duration16h 59mAverage Duration
Ticket$132Cheapest Price
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Comparing Your Travel Options

Map of how to get from North Carolina to St. Louis.ExpandLaunch map view
  • Distance: 595.4 mi
  • Duration: 4h 5m

What companies run services between North Carolina, USA and St. Louis, MO, USA?

American Airlines, Southwest Airlines, and Delta fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a bus from Charlotte Bus Station to St Louis Bus Station via Atlanta Downtown, Civic Center Station, Garnett Station, and Atlanta Bus Station in around 16h 59m.

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