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How to get fromNorth Charleston to Durhamby train (Amtrak), bus (Greyhound), car, plane, or train

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There are 7 ways to get from North Charleston to Durham by train (Amtrak), bus (Greyhound), car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Charleston Amtrak Station to Selma Stationtrain train Palmetto
    2. Take the train from Selma Station to Durham Amtrak Stationtrain train Carolinian
    6h 22m
    $74–167

  2. Drive  256.2 mi

    cheapest
    1. Drive from North Charleston to Durhamcar car 256.2 mi
    5h 37m
    $47–68

  3. Bus (Greyhound)

    1. Take the bus from Charleston Bus Station to Raleigh Bus Stationbus bus Greyhound US0645S
    9h 20m
    $58–108

  4. Fly to Raleigh-Durham International Airport

    1. Fly from Charleston International Airport (CHS) to Raleigh-Durham International Airport (RDU)plane plane CHS - RDU
    5h 46m
    $258–608

  5. Bus via Camden

    1. Take the bus from Charleston Bus Station to Camdenbus bus Greyhound US0641S
    2. Take the bus from Camden to Durhambus bus Augusta
    11h 40m
    $74–123

  6. Fly to Piedmont Triad International Airport, train

    1. Fly from Charleston International Airport (CHS) to Piedmont Triad International Airport (GSO)plane plane CHS - GSO
    2. Take the train from Greensboro to Durham Amtrak Stationtrain train
    6h 32m
    $130–722

  7. Fly to Charlotte Douglas International Airport, train

    1. Fly from Charleston International Airport (CHS) to Charlotte Douglas International Airport (CLT)plane plane CHS - CLT
    2. Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain train
    7h 4m
    $101–543

North Charleston to Durham by train (Amtrak)

Calendar7Weekly Trains
Duration6h 22mAverage Duration
Ticket$74Cheapest Price
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Questions & Answers

Map of how to get from North Charleston to Durham.ExpandLaunch map view
  • Distance: 280.6 mi
  • Duration: 6h 22m

What companies run services between North Charleston, SC, USA and Durham, NC, USA?

You can take a train from Charleston Amtrak Station to Durham Amtrak Station via Selma Station in around 6h 22m. Alternatively, Greyhound USA operates a bus from Charleston Bus Station to Raleigh Bus Station once daily. Tickets cost $50–110 and the journey takes 7h 45m.

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